Hartshorne M F, Graham G, Lancaster J, Berger D
J Nucl Med. 1985 Mar;26(3):272-7.
Simultaneous digital acquisition of [67Ga] and [99mTc]MDP images, and subsequent division of the first by the second to produce a parametric ratio image (G/T), is employed to characterize the relative localization of the two radiopharmaceuticals in early rabbit tibia Staphloccocus aureus osteomyelitis and fracture repair. Images obtained during the first 48 hr of each condition show preferential 67Ga accumulation probably reflecting an initial inflammatory response while G/T images at 5-7 days show predominance of the bone-seeking scan agent, which may indicate that the dominant process is osteoblastic repair.
同时进行[67Ga]和[99mTc]MDP图像的数字采集，随后将前者除以后者以生成参数比值图像（G/T），用于表征两种放射性药物在兔早期胫骨金黄色葡萄球菌骨髓炎和骨折修复中的相对定位。在每种情况的最初48小时内获得的图像显示67Ga优先积聚，这可能反映了初始炎症反应，而5 - 7天的G/T图像显示亲骨性扫描剂占主导，这可能表明主要过程是成骨细胞修复。
