Kadıoğlu Şimşek Gülsüm, Kutman H Gözde Kanmaz, Canpolat Fuat Emre, Büyüktiryaki Mehmet, Üstün Yaprak Engin
Department of Neonatology, NICU, Zekai Tahir Burak Health Practice and Research Center, University of Medical Sciences, 06240, Hamamönü, Altındağ, Ankara, Turkey.
Department of Obstetrics and Gyneacology, Chief of Hospital, Zekai Tahir Burak Health Practice and Research Center, University of Medical Sciences, 06240, Hamamönü, Altındağ, Ankara, Turkey.
Int J Pediatr Otorhinolaryngol. 2020 Jan;128:109691. doi: 10.1016/j.ijporl.2019.109691. Epub 2019 Sep 19.
The objective of this study was to establish the local incidence of hearing screening failure rate in newborns with all three stages of hypoxic ischemic encephalopathy (HIE).
This retrospective cohort study was undertaken in a tertiary neonatal intensive care unit. Medical records and hearing secreening test results were collected for two years.
One hundred and ninety seven infants diagnosed with HIE, 20 of them died, 177 screened. Thirty five of 177 (19%) infants failed in screening test for hearing. Screening failure rate was 10/51 (19%), 20/105 (19%) and 5/21 (23%) in stage 1, 2 and 3, respectively and did not differ between HIE stages (p = 0.88). Furthermore failure rates were similar between infants who received therapeutic hypothermia or not (20% vs 19%, p = 0.84).
Hearing screening failure rate in HIE is quite high even in Stage 1 infants. Management and treatment of these infants should be made carefully concerning additional risks for hearing loss and long term follow-up even in Stage 1 HIE infants should be planned strictly.
本研究的目的是确定患有三个阶段缺氧缺血性脑病（HIE）的新生儿听力筛查失败率的局部发病率。
这项回顾性队列研究在一家三级新生儿重症监护病房进行。收集了两年的病历和听力筛查测试结果。
197名诊断为HIE的婴儿，其中20名死亡，177名接受筛查。177名婴儿中有35名（19%）听力筛查失败。1期、2期和3期的筛查失败率分别为10/51（19%）、20/105（19%）和5/21（23%），在HIE各阶段之间无差异（p = 0.88）。此外，接受或未接受治疗性低温治疗的婴儿之间的失败率相似（20%对19%，p = 0.84）。
即使是1期婴儿，HIE的听力筛查失败率也相当高。对于这些婴儿的管理和治疗应谨慎考虑听力损失的额外风险，即使是1期HIE婴儿也应严格规划长期随访。
