Division of Kidney, Urologic, and Hematologic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Division of Nephrology, Department of Medicine, University of British Columbia, British Columbia, Canada.
Kidney Int. 2019 Nov;96(5):1071-1076. doi: 10.1016/j.kint.2019.06.024. Epub 2019 Aug 2.
In June 2018, the National Institute of Diabetes and Digestive and Kidney Diseases and the National Institute of Environmental Health Sciences sponsored a workshop to identify research gaps in an increasingly common form of chronic kidney disease in agricultural communities, often termed "CKDu." The organizers invited a broad range of experts who provided diverse expertise and perspectives, many of whom had never addressed this particular epidemic. Discussion was focused around selected topics, including identifying and mitigating barriers to research in CKDu, creating a case definition, and defining common data elements. All hypotheses regarding etiology were entertained, and meeting participants discussed potential research strategies, choices in study design, and novel tools that may prove useful in this disease. Achievements of the workshop included robust cross-disciplinary discussion and preliminary planning of research goals and design. Specific challenges in implementing basic and clinical research and interventions in low- and middle-income countries were recognized. A balanced approach to leveraging local resources and capacity building without overreaching was emphasized.
2018 年 6 月，美国国家糖尿病、消化和肾脏疾病研究所和国家环境卫生科学研究所联合主办了一次研讨会，旨在确定农业社区中一种日益常见的慢性肾脏病形式（通常称为“CKDu”）的研究空白。组织者邀请了广泛的专家，他们提供了不同的专业知识和观点，其中许多人以前从未处理过这种特定的流行病。讨论集中在选定的主题上，包括确定和克服 CKDu 研究的障碍、创建病例定义以及定义通用数据元素。所有关于病因的假设都被考虑在内，会议参与者讨论了潜在的研究策略、研究设计选择以及可能对该疾病有用的新工具。研讨会的成果包括跨学科的激烈讨论以及对研究目标和设计的初步规划。会议还认识到在中低收入国家实施基础和临床研究及干预措施所面临的具体挑战。强调了在不过度扩张的情况下，平衡利用当地资源和能力建设的方法。
