用于深度探测散射介质的空间角滤波器（SAF）成像装置。
Spatio-angular filter (SAF) imaging device for deep interrogation of scattering media.
作者信息
Pandya Aditya, Schelkanova Irina, Douplik Alexandre
机构信息
Department of Physics, Ryerson University, Toronto, ON, M5B 2K3, Canada.
Institute for Biomedical Engineering, Science and Technology (iBEST), St. Michael's Hospital, Toronto, ON, M5B 1W8, Canada.
出版信息
Biomed Opt Express. 2019 Aug 20;10(9):4656-4663. doi: 10.1364/BOE.10.004656. eCollection 2019 Sep 1.
Optical microscopy is limited to shallow interrogation depths as high-resolution imaging in scattering media is challenging. Current methods require complex and expensive experimental setup or suffer from low resolution. Through gating of photons exiting the scattering media using a restricted numerical aperture (NA) fiber optic plate (FOP), we establish a novel spatio-angular filter imaging device that allows deeper imaging in scattering media. Using dilutions of Intralipid (1-4 v/v%) and a USAF resolution target, it is shown that by reducing the NA of the FOP from 0.55 to 0.17, the interrogation depth improves ~2 times using trans-illumination.
光学显微镜限于浅探测深度，因为在散射介质中进行高分辨率成像具有挑战性。当前方法需要复杂且昂贵的实验装置，或者分辨率较低。通过使用受限数值孔径（NA）的光纤板（FOP）对离开散射介质的光子进行选通，我们建立了一种新型的空间角滤波成像装置，该装置能够在散射介质中进行更深层的成像。使用不同稀释度的英脱利匹特（1 - 4 v/v%）和美国空军分辨率靶标，结果表明，通过将FOP的NA从0.55降低到0.17，采用透照法时探测深度提高了约2倍。
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