Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI, United States.
Department of Pediatric and Adolescent Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI, United States.
Dis Mon. 2020 Apr;66(4):100886. doi: 10.1016/j.disamonth.2019.100886. Epub 2019 Sep 27.
Asthma is a complex condition that affects 14% of the world's children and the approach to management includes both pharmacologic as well as non-pharmacologic strategies including attention to complex socioeconomic status phenomena. After an historical consideration of asthma, allergic and immunologic aspects of asthma in children and adolescents are presented. Concepts of socioeconomic aspects of asthma are considered along with environmental features and complications of asthma disparities. Also reviewed are links of asthma with mental health disorders, sleep disturbances and other comorbidities. A stepwise approach to asthma management is discussed that includes pharmacologic and non-pharmacologic strategies in the pediatric population. The role of immunotherapy and use of various immunomodulators are considered as well.
哮喘是一种复杂的疾病，影响着全球 14%的儿童。其管理方法包括药物和非药物策略，包括关注复杂的社会经济地位现象。在对哮喘的历史回顾之后，介绍了儿童和青少年哮喘的过敏和免疫学方面。还考虑了哮喘的社会经济方面的概念，以及环境特征和哮喘差异的并发症。还回顾了哮喘与心理健康障碍、睡眠障碍和其他合并症的关联。讨论了一种针对哮喘管理的逐步方法，包括儿科人群中的药物和非药物策略。还考虑了免疫疗法和各种免疫调节剂的使用。
