Gribsholt Sigrid Bjerge, Pedersen Lars, Richelsen Bjørn, Thomsen Reimar Wernich
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Clin Epidemiol. 2019 Sep 11;11:845-854. doi: 10.2147/CLEP.S214909. eCollection 2019.
Health care databases may be a valuable source for epidemiological research in obesity, if diagnoses are valid. We examined the validity and completeness of International Classification of Diseases, 10th revision [ICD-10] diagnosis coding for overweight/obesity in Danish hospitals.
We linked data from the Danish National Patient Registry on patients with a hospital diagnosis code of overweight/obesity (ICD-10 code E66) with computerized height and weight measurements made during hospital contacts in the Central Denmark Region Clinical Information System. We computed the positive predictive value (PPV) of the IDC-10 diagnosis of overweight/obesity, using a documented body mass index (BMI) ≥25 kg/m as gold standard. We also examined the completeness of obesity/overweight diagnosis coding among all patients recorded with BMI ≥25 kg/m.
Of all 19,672 patients registered with a first diagnosis code of overweight/obesity in the National Patient Registry, 17,351 patients (88.2%) had any BMI measurement recorded in the Central Denmark Region Clinical Information System, and 17,240 patients (87.6%) had a BMI ≥25 kg/m, yielding a PPV of 87.6% (95% CI: 87.2-88.1). The PPV was slightly higher for primary diagnosis codes of overweight/obesity: 94.1% (95% CI: 93.3-94.8) than for secondary diagnosis codes: 86.1% (95% CI: 85.6-86.6). The PPV increased with higher patient age: from 75.3% (95% CI: 73.8-76.9) in those aged 18-29 years to 94.7% (95% CI: 92.6-96.9) in patients aged 80 years and above. Completeness of obesity/overweight diagnosis coding among patients recorded with BMI ≥25 kg/m was only 10.9% (95% CI: 10.8-11.0).
Our findings indicate a high validity of the ICD-10 code E66 for overweight/obesity when recorded; however, completeness of coding was low. Nonetheless, ICD-10 discharge codes may be a suitable source of data on overweight/obesity for epidemiological research.
如果诊断有效,医疗保健数据库可能是肥胖症流行病学研究的宝贵资源。我们检查了丹麦医院中第十版国际疾病分类[ICD-10]超重/肥胖诊断编码的有效性和完整性。
我们将丹麦国家患者登记处中诊断代码为超重/肥胖(ICD-10代码E66)的患者数据与丹麦中部地区临床信息系统中住院期间进行的计算机化身高和体重测量数据相链接。我们以记录的体重指数(BMI)≥25kg/m²作为金标准,计算了ICD-10超重/肥胖诊断的阳性预测值(PPV)。我们还检查了所有记录的BMI≥25kg/m²患者中肥胖/超重诊断编码的完整性。
在国家患者登记处首次诊断代码为超重/肥胖的所有19672名患者中,17351名患者(88.2%)在丹麦中部地区临床信息系统中有任何BMI测量记录,17240名患者(87.6%)的BMI≥25kg/m²,PPV为87.6%(95%置信区间:87.2 - 88.1)。超重/肥胖的主要诊断代码的PPV略高于次要诊断代码:分别为94.1%(95%置信区间:93.3 - 94.8)和86.1%(95%置信区间:85.6 - 86.6)。PPV随着患者年龄的增加而增加:18 - 29岁患者中为75.3%(95%置信区间:73.8 - 76.9),80岁及以上患者中为94.7%(95%置信区间:92.6 - 96.9)。BMI≥25kg/m²患者中肥胖/超重诊断编码的完整性仅为10.9%(95%置信区间:10.8 - 11.0)。
我们的研究结果表明,记录的ICD-10代码E66用于超重/肥胖时具有较高的有效性;然而,编码的完整性较低。尽管如此,ICD-10出院代码可能是超重/肥胖流行病学研究的合适数据来源。