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介入医学中炎症细胞的光学分子成像——一种新兴策略。

Optical Molecular Imaging of Inflammatory Cells in Interventional Medicine-An Emerging Strategy.

作者信息

Birch Gavin P, Campbell Thane, Bradley Mark, Dhaliwal Kevin

机构信息

EaStChem School of Chemistry, University of Edinburgh, Edinburgh, United Kingdom.

Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.

出版信息

Front Oncol. 2019 Sep 12;9:882. doi: 10.3389/fonc.2019.00882. eCollection 2019.

DOI:10.3389/fonc.2019.00882
PMID:31572676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6751259/
Abstract

The optical molecular imaging of inflammation is an emerging strategy for interventional medicine and diagnostics. The host's inflammatory response and adaptation to acute and chronic diseases provides unique signatures that have the potential to guide interventions. Thus, there are emerging a suite of molecular imaging and sensing approaches for a variety of targets in this area. This review will focus on two key cellular orchestrators that dominate this area, neutrophils and macrophages, with recent developments in molecular probes and approaches discussed.

摘要

炎症的光学分子成像技术是介入医学和诊断学领域中一种新兴的策略。宿主对急慢性疾病的炎症反应和适应性表现出独特的特征，这些特征有可能指导干预措施。因此，针对该领域各种靶点，涌现出了一系列分子成像和传感方法。本综述将聚焦于主导该领域的两个关键细胞协调因子——中性粒细胞和巨噬细胞，并讨论分子探针和方法的最新进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/ea3f15fdcf3b/fonc-09-00882-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/817118f071f1/fonc-09-00882-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/57e4ebc15862/fonc-09-00882-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/c0c55b76d1a8/fonc-09-00882-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/416385599911/fonc-09-00882-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/0fa5bc605c84/fonc-09-00882-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/51fc35bbc77f/fonc-09-00882-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/675cc3592beb/fonc-09-00882-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/6842d6774a45/fonc-09-00882-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/ea3f15fdcf3b/fonc-09-00882-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/817118f071f1/fonc-09-00882-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/57e4ebc15862/fonc-09-00882-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/c0c55b76d1a8/fonc-09-00882-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/416385599911/fonc-09-00882-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/0fa5bc605c84/fonc-09-00882-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/51fc35bbc77f/fonc-09-00882-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/675cc3592beb/fonc-09-00882-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/6842d6774a45/fonc-09-00882-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c738/6751259/ea3f15fdcf3b/fonc-09-00882-g0009.jpg

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