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[膜增生性肾小球肾炎与肺炎支原体感染]

[Membranoproliferative glomerulonephritis and Mycoplasma pneumoniae infection].

作者信息

Cochat P, Colon S, Bosshard S, Zech P, Traeger J

出版信息

Arch Fr Pediatr. 1985 Jan;42(1):29-31.

PMID:3157358
Abstract

On the occasion of a new case and review of 9 others in the literature, the authors seek to establish the hallmarks of the nephritis occurring after M. pneumoniae infection. It often consists of an acute nephritic syndrome, 10 to 40 days after a respiratory tract infection; hematological abnormalities are not constant. Histological examination of the kidney shows a type I membranoproliferative glomerulonephritis in 2, dense deposit disease in 2 and tubulo-interstitial nephritis in one. Immunofluorescence studies have shown the microbial antigen 3 times out of 4. Specific antibiotherapy does not charge the prognosis of the extrarespiratory manifestations, for which an immunologic mechanism is likely.

摘要

在出现一例新病例并回顾文献中其他9例病例的情况下,作者试图确定肺炎支原体感染后发生的肾炎的特征。它通常由急性肾炎综合征组成,发生在呼吸道感染后10至40天;血液学异常并不恒定。肾脏组织学检查显示,2例为I型膜增生性肾小球肾炎,2例为致密物沉积病,1例为肾小管间质性肾炎。免疫荧光研究在4次中有3次显示出微生物抗原。特异性抗生素治疗并不能改变呼吸外表现的预后,呼吸外表现可能存在免疫机制。

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