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在一名急性肾小球肾炎患者的肾组织中采用聚合酶链反应检测肺炎支原体。

Mycoplasma pneumoniae detection with PCR in renal tissue of a patient with acute glomerulonephritis.

作者信息

Laso María del Carmen, Cadario María Estela, Haymes Laura, Grimoldi Irene, Balbarrey Ziomara, Casanueva Enrique

机构信息

Nephrology Department, Hospital Municipal del Niño, Granada 4175 (1754), San Justo, Buenos Aires Province, Argentina.

出版信息

Pediatr Nephrol. 2006 Oct;21(10):1483-6. doi: 10.1007/s00467-006-0179-2. Epub 2006 Jul 4.

DOI:10.1007/s00467-006-0179-2
PMID:16819643
Abstract

Renal disease concurrent with a Mycoplasma pneumoniae infection is uncommon. In this report we describe the clinical outcome of a 6-year-old patient who presented with a rapidly progressive glomerulonephritis that required dialysis. A kidney biopsy was performed, and the results revealed membranoprolipherative glomerulonephritis. The IgM serology was positive, and M. pneumoniae DNA was detected in a renal biopsy sample using a nested-PCR assay. The outcome was good.

摘要

并发肺炎支原体感染的肾脏疾病并不常见。在本报告中，我们描述了一名6岁患者的临床结局，该患者表现为快速进展性肾小球肾炎，需要进行透析。进行了肾活检，结果显示为膜增生性肾小球肾炎。IgM血清学呈阳性，使用巢式PCR检测法在肾活检样本中检测到肺炎支原体DNA。结局良好。

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Mycoplasma pneumoniae detection with PCR in renal tissue of a patient with acute glomerulonephritis.在一名急性肾小球肾炎患者的肾组织中采用聚合酶链反应检测肺炎支原体。
Pediatr Nephrol. 2006 Oct;21(10):1483-6. doi: 10.1007/s00467-006-0179-2. Epub 2006 Jul 4.
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Mycoplasma pneumoniae from the Respiratory Tract and Beyond.来自呼吸道及其他部位的肺炎支原体
Clin Microbiol Rev. 2017 Jul;30(3):747-809. doi: 10.1128/CMR.00114-16.
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Favorable outcome in a case of Mycoplasma pneumoniae-associated crescentic glomerulonephritis.支原体肺炎相关性新月体性肾小球肾炎一例疗效良好。

本文引用的文献

1
Mycoplasma pneumoniae and its role as a human pathogen.肺炎支原体及其作为人类病原体的作用。
Clin Microbiol Rev. 2004 Oct;17(4):697-728, table of contents. doi: 10.1128/CMR.17.4.697-728.2004.
2
Acute nephritis and respiratory tract infection caused by Mycoplasma pneumoniae: case report and review of the literature.肺炎支原体引起的急性肾炎和呼吸道感染：病例报告及文献复习
Pediatr Infect Dis J. 2003 Dec;22(12):1103-6. doi: 10.1097/01.inf.0000104531.58503.90.
3
Pneumonia-associated acute glomerulonephritis.肺炎相关性急性肾小球肾炎
Pediatr Nephrol. 2010 Sep;25(9):1765-9. doi: 10.1007/s00467-010-1491-4. Epub 2010 Mar 25.
Clin Nephrol. 2002 Mar;57(3):175-82. doi: 10.5414/cnp57175.
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Mycoplasma pneumoniae-associated nephritis in children.儿童支原体肺炎相关性肾炎
Pediatr Nephrol. 1999 Jan;13(1):39-44. doi: 10.1007/s004670050559.
5
Antibody to streptococcal zymogen in the serum of patients with acute glomerulonephritis: a multicentric study.急性肾小球肾炎患者血清中抗链球菌酶原抗体：一项多中心研究
Kidney Int. 1998 Aug;54(2):509-17. doi: 10.1046/j.1523-1755.1998.00012.x.
6
Diagnosis of Mycoplasma pneumoniae infection in autopsy and open-lung biopsy tissues by nested PCR.通过巢式聚合酶链反应对尸检和开胸肺活检组织中的肺炎支原体感染进行诊断。
J Clin Microbiol. 1998 Apr;36(4):1151-3. doi: 10.1128/JCM.36.4.1151-1153.1998.
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Acute interstitial nephritis associated with Mycoplasma pneumoniae infection.与肺炎支原体感染相关的急性间质性肾炎。
Nephrol Dial Transplant. 1994;9(5):564-6. doi: 10.1093/ndt/9.5.564.
8
DNA probes and PCR in diagnosis of mycoplasma infections.用于支原体感染诊断的DNA探针与聚合酶链反应
Mol Cell Probes. 1994 Dec;8(6):497-511. doi: 10.1006/mcpr.1994.1071.
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Anti-streptolysin O titer, fifty-five years after Todd: a reappraisal of its clinical significance.
Boll Ist Sieroter Milan. 1988;67(2):162-4.
10
[Membranoproliferative glomerulonephritis and Mycoplasma pneumoniae infection].[膜增生性肾小球肾炎与肺炎支原体感染]
Arch Fr Pediatr. 1985 Jan;42(1):29-31.