Chiu R C, Blundell P E, Scott H J, Cain S
Ann Thorac Surg. 1979 Oct;28(4):317-22. doi: 10.1016/s0003-4975(10)63128-1.
In 50 patients undergoing cardiac operation, hypothermic cardioplegic solution was infused into the root of the aorta immediately after aortic cross-clamping. Cardiac standstill was achieved within 1 to 3 minutes. However, monitoring of intramyocardial temperature with a needle thermistor revealed that such core cooling is unpredictable (the intramyocardial temperature achieved ranged from 7 degrees to 33 degrees C), unstable (this temperature can rise at more than 0.5 degrees C per minute), and uneven (a difference of up to 17 degrees C was observed between the intramyocardial temperature of the anterior and posterior left ventricular sites). The area supplied by the stenotic coronary artery was least protected. Monitoring of intramyocardial temperature enables one to know when supplementary cooling is indicated. We conclude that widespread differences in this temperature during cardiac operation make monitoring advisable for optimal myocardial protection.
在50例接受心脏手术的患者中,在主动脉交叉钳夹后立即将低温心脏停搏液注入主动脉根部。1至3分钟内实现心脏停搏。然而,用针式热敏电阻监测心肌内温度发现,这种核心降温是不可预测的(心肌内温度范围为7摄氏度至33摄氏度)、不稳定的(该温度每分钟可升高超过0.5摄氏度)且不均匀的(左心室前后部位的心肌内温度相差高达17摄氏度)。狭窄冠状动脉供血的区域受保护最少。监测心肌内温度能让人们知道何时需要补充降温。我们得出结论,心脏手术期间这种温度存在广泛差异,因此为实现最佳心肌保护,监测是可取的。