Albrecht G
Hautarzt. 1985 Feb;36(2):77-82.
Lithium plays an important role in the treatment and prophylaxis of affective psychoses. Taking lithium-containing drugs by mouth can cause side effects on the skin, although severe side effects are rare. Acneiform dermatoses have been most frequently described. In addition, when taking lithium continuously, psoriasis can be triggered or worsened and the psoriasis tends to be resistant to treatment. Maculo papular eruptions, ulcers, keratosis pilaris like folliculitis, exfoliative dermatitis, dermatitis herpetiformis like eruption, and hair loss have been described. Possibly the blood level of lithium plays a decisive role in developing a dermatosis. If the skin side effect is mild, the dermatosis should be treated topically. If the dermatoses under lithium treatment are severe, a reduction in the lithium dosage should possibly be discussed with the psychiatrist. Only rarely does lithium have to be entirely discontinued.
锂在情感性精神病的治疗和预防中起着重要作用。口服含锂药物可能会对皮肤产生副作用，尽管严重副作用很少见。最常描述的是痤疮样皮疹。此外，持续服用锂时，可能会引发或加重银屑病，且银屑病往往对治疗有抵抗性。还描述过斑丘疹、溃疡、毛发角化病样毛囊炎、剥脱性皮炎、疱疹样皮炎样皮疹和脱发。锂的血药浓度可能在皮肤病的发生中起决定性作用。如果皮肤副作用较轻，应局部治疗皮肤病。如果锂治疗期间的皮肤病严重，可能应与精神科医生讨论减少锂的剂量。只有极少数情况下才必须完全停用锂。
