Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Faculty of Chemistry, Northeast Normal University, Changchun 130024, China.
Chem Commun (Camb). 2019 Oct 25;55(83):12519-12522. doi: 10.1039/c9cc05802h. Epub 2019 Oct 2.
A novel Zn(OAc)-catalyzed three-component tandem cyclization reaction of isocyanides, α-diazoketones and anhydrides has been developed. The reaction demonstrates the wide scope of substrates and provides a novel and efficient strategy for the synthesis of polysubstituted maleimides from readily available substrates in a single step.
一种新型的 Zn(OAc)-催化的异氰化物、α-重氮酮和酸酐的三组分串联环化反应已经被开发出来。该反应展示了广泛的底物范围，并提供了一种从易得的底物一步合成多取代马来酰亚胺的新颖而有效的策略。
