Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Institute of Medical Engineering, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.
Cardiovasc Intervent Radiol. 2020 Feb;43(2):331-338. doi: 10.1007/s00270-019-02347-x. Epub 2019 Oct 2.
PURPOSE: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI). MATERIALS AND METHODS: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3-4 mm; length: 11-38 mm) and materials (stainless steel, platinum-chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale. RESULTS: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts. CONCLUSION: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.
目的:与临床计算机断层扫描(CT)和磁共振成像(MRI)相比,展示磁粒子成像(MPI)在支架管腔成像中的潜力。
材料与方法:在临床前 MPI 扫描仪上对填充示踪剂的八个支架血管模型和每个直径的一个填充示踪剂的非支架参考模型进行成像:将八个不同尺寸(直径:3-4 毫米;长度:11-38 毫米)和材料(不锈钢、铂-铬)的市售冠状动脉支架植入硅胶血管模型中。为了进行比较,所有血管模型也通过 MRI 和 CT 进行可视化。两名放射科医生使用 5 分制评分评估图像中的支架引起的伪影。
结果:MPI 实现了对所有支架血管模型的无支架引起伪影可视化。相比之下,MRI 和 CT 图像显示了多种支架引起的伪影。
结论:鉴于其临床应用,MPI 有可能克服 MRI 和 CT 在支架管腔可视化方面的缺点。
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