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在磁粒子成像和磁共振成像期间对缩窄治疗用主动脉支架进行加热:一项比较性的体外研究。

Heating of an Aortic Stent for Coarctation Treatment During Magnetic Particle Imaging and Magnetic Resonance Imaging-A Comparative In Vitro Study.

机构信息

Department of Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.

Institute of Medical Engineering, University of Lübeck, Lübeck, Germany.

出版信息

Cardiovasc Intervent Radiol. 2021 Jul;44(7):1109-1115. doi: 10.1007/s00270-021-02795-4. Epub 2021 Mar 15.

DOI:10.1007/s00270-021-02795-4
PMID:33723668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8189960/
Abstract

PURPOSE

To evaluate heating of a redilatable stent for the treatment of aortic coarctation in neonates and small children in the new imaging modality magnetic particle imaging and established magnetic resonance imaging.

MATERIALS AND METHODS

The cobalt-chromium stent (BabyStent, OSYPKA AG, Rheinfelden, Germany) has a stent design which allows for redilatation and adjustment of the diameter from 6 to 16 mm for a use in aortic coarctation. The stent loses its radial integrity while opening at predetermined breaking points at a diameter of 14 mm or 16 mm, respectively. We measured the temperature increase in the stent at different diameters during 7-min magnetic particle imaging and magnetic resonance imaging scans with fiber optic thermometers under static conditions surrounded by air. In magnetic particle imaging, stents with diameters from 6 to 16 mm were tested while in magnetic resonance imaging only stents with diameters of 6 mm and 14 mm were investigated exemplarily.

RESULT

In magnetic particle imaging, the measured temperature differences increased up to 4.7 K with growing diameters, whereas the opened stents with discontinuous struts at 14 and 16 mm showed only minimal heating of max. 0.5 K. In contrast to magnetic particle imaging, our measurements showed no heating of the stents during magnetic resonance imaging under identical conditions.

CONCLUSION

The BabyStent did show only slight heating in magnetic particle imaging and no detectable temperature increase in magnetic resonance imaging.

摘要

目的

在新的成像方式——磁粒子成像和已建立的磁共振成像中,评估用于治疗新生儿和幼儿主动脉缩窄的可膨胀支架的加热情况。

材料和方法

钴铬支架(BabyStent,OSYPKA AG,Rheinfelden,德国)具有支架设计,允许在主动脉缩窄的情况下从 6 毫米至 16 毫米进行再扩张和直径调整。支架在预定的断裂点打开时会失去其径向完整性,分别在直径为 14 毫米或 16 毫米处。我们使用光纤温度计在静态条件下在空气中进行了 7 分钟的磁粒子成像和磁共振成像扫描,测量了不同直径的支架的温度升高。在磁粒子成像中,测试了直径为 6 毫米至 16 毫米的支架,而在磁共振成像中仅测试了直径为 6 毫米和 14 毫米的支架。

结果

在磁粒子成像中,随着直径的增大,测量到的温差增加了 4.7K,而在 14 和 16 毫米处具有不连续支柱的打开支架仅显示出最大 0.5K 的最小加热。与磁粒子成像相比,在相同条件下进行磁共振成像时,我们的测量结果显示支架没有加热。

结论

BabyStent 在磁粒子成像中仅显示出轻微的加热,在磁共振成像中没有检测到可察觉的温度升高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/d995383d968f/270_2021_2795_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/2f2bbd884f64/270_2021_2795_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/4a2d47e820fa/270_2021_2795_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/975c52607d72/270_2021_2795_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/b6c60f851c2d/270_2021_2795_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/6bdbe3939b2a/270_2021_2795_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/99d20eb0320a/270_2021_2795_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/d995383d968f/270_2021_2795_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/2f2bbd884f64/270_2021_2795_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/4a2d47e820fa/270_2021_2795_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/975c52607d72/270_2021_2795_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/b6c60f851c2d/270_2021_2795_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/6bdbe3939b2a/270_2021_2795_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/99d20eb0320a/270_2021_2795_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6849/8189960/d995383d968f/270_2021_2795_Fig7_HTML.jpg

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