Spuentrup Elmar, Ruebben Alexander, Mahnken Andreas, Stuber Matthias, Kölker Christian, Nguyen Trung Hieu, Günther Rolf W, Buecker Arno
Department of Diagnostic Radiology, Technical University of Aachen, Aachen, Germany.
Circulation. 2005 Mar 1;111(8):1019-26. doi: 10.1161/01.CIR.0000156462.97532.8F. Epub 2005 Feb 21.
Coronary in-stent restenosis cannot be directly assessed by magnetic resonance angiography (MRA) because of the local signal void of currently used stainless steel stents. The aim of this study was to investigate the potential of a new, dedicated, coronary MR imaging (MRI) stent for artifact-free, coronary MRA and in-stent lumen and vessel wall visualization.
Fifteen prototype stents were deployed in coronary arteries of 15 healthy swine and investigated with a double-oblique, navigator-gated, free-breathing, T2-prepared, 3D cartesian gradient-echo sequence; a T2-prepared, 3D spiral gradient-echo sequence; and a T2-prepared, 3D steady-state, free-precession coronary MRA sequence. Furthermore, black-blood vessel wall imaging by a dual-inversion-recovery, turbo spin-echo sequence was performed. Artifacts of the stented vessel segment and signal intensities of the coronary vessel lumen inside and outside the stent were assessed. With all investigated sequences, the vessel lumen and wall could be visualized without artifacts, including the stented vessel segment. No signal intensity alterations inside the stent when compared with the vessel lumen outside the stent were found.
The new, coronary MRI stent allows for completely artifact-free coronary MRA and vessel wall imaging.
由于目前使用的不锈钢支架会产生局部信号缺失，冠状动脉支架内再狭窄无法通过磁共振血管造影（MRA）直接评估。本研究的目的是探讨一种新型专用冠状动脉磁共振成像（MRI）支架在实现无伪影冠状动脉MRA以及支架内管腔和血管壁可视化方面的潜力。
将15个原型支架植入15只健康猪的冠状动脉中，采用双斜位、导航门控、自由呼吸、T2加权、三维笛卡尔梯度回波序列；T2加权、三维螺旋梯度回波序列；以及T2加权、三维稳态、自由进动冠状动脉MRA序列进行研究。此外，还采用双反转恢复快速自旋回波序列进行黑血血管壁成像。评估支架置入血管段的伪影以及支架内外冠状动脉管腔的信号强度。在所有研究序列中，包括支架置入血管段在内的血管管腔和血管壁均可无伪影显示。与支架外血管管腔相比，未发现支架内信号强度改变。
新型冠状动脉MRI支架可实现完全无伪影的冠状动脉MRA和血管壁成像。
