[磁粒子成像：从研究到临床应用前景]
[Magnetic particle imaging : From research to the prospect of clinical use].
作者信息
Gräser Matthias, Wegner Franz, Schumacher Jonas, Ahlborg Mandy, Gräfe Ksenija, Aderhold Eric, Blancke Soares Yvonne, Lüdtke-Buzug Kerstin, Neumann Alexander, Stagge Pascal, Wei Huimin, Ackers Justin, Buzug Thorsten M
机构信息
Fraunhofer Einrichtung für Individualisierte und Zellbasierte Medizintechnik, Mönkhofer Weg 239a, 23562, Lübeck, Deutschland.
Institut für Medizintechnik, Universität zu Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland.
出版信息
Radiologie (Heidelb). 2022 Jun;62(6):496-503. doi: 10.1007/s00117-022-01011-9. Epub 2022 May 20.
BACKGROUND
Magnetic particle imaging offers far-reaching potential with a unique range of applications.
OBJECTIVES
Identification of application scenarios with added value for clinical use.
METHODS
Overview of previous application scenarios in phantom and small animal models, evaluation of dual-use potential.
RESULTS
With its unique application profile, magnetic particle imaging offers a solution for clinical use where common, established imaging techniques reach their limits. As a tracer imaging technique, it is particularly characterized by its high speed, sensitivity and contrast-to-noise ratio. The low magnetic fields and low power consumption allow imaging to be mobile and taken to locations that were previously inaccessible.
CONCLUSION
Magnetic particle imaging has seen rapid development in recent years. The applications demonstrated in the small animal model and phantom were able to support the versatility and added value of the method. With the availability of human imaging systems, the technology must face clinical verification studies.
背景
磁粒子成像具有广泛的潜力，拥有一系列独特的应用。
目的
确定对临床应用具有附加价值的应用场景。
方法
概述先前在体模和小动物模型中的应用场景，评估两用潜力。
结果
磁粒子成像凭借其独特的应用特性，为临床应用提供了一种解决方案，适用于常规成熟成像技术达到其极限的情况。作为一种示踪剂成像技术，其特别之处在于具有高速度、高灵敏度和高对比度噪声比。低磁场和低功耗使成像能够实现移动性，并可带到以前无法到达的地点。
结论
磁粒子成像近年来发展迅速。在小动物模型和体模中展示的应用能够支持该方法的多功能性和附加价值。随着人体成像系统的出现，该技术必须面对临床验证研究。
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