Department of Medicine, Division of Cardiology, Weill Cornell Medical Center, New York, New York.
J Cardiovasc Electrophysiol. 2019 Dec;30(12):3057-3067. doi: 10.1111/jce.14209. Epub 2019 Oct 13.
Left atrial tachycardias (ATs) most commonly occur after catheter or surgical ablation of atrial fibrillation and in patients with atrial myopathies. Pre-existing scar in the left atrium (LA) can result in complex circuits, sometimes with narrow channels that can be detected with high-resolution mapping. The most common forms of macroreentrant AT from the LA are variants of peri-mitral and roof-dependent reentry. Localized reentrant rhythms occur in the setting of fibrosis that gives rise to slow conduction and may occur adjacent to areas of prior ablation. The approach to treating these ATs involves first identifying the left atrial origin, defining the tachycardia circuit - which can be facilitated by ultrahigh density mapping and entrainment - and selecting a suitable isthmus to target for ablation. An important endpoint in ablating left atrial flutters is to establish and confirm bidirectional line of the block. Challenges in ablating these ATs include the presence of multiple tachycardias, defining circuits with complex activation patterns and achieving durable lines of block, particularly in the lateral mitral isthmus. Progress in treating these arrhythmias has come from new mapping technologies and the recognition of epicardial connections that allow for persistent conduction across ablation lesions. Also, advances in delivering energy to obtain complete transmural lesions promise to improve the long-term success of ablating ATs from the LA.
左房心动过速(ATs)最常发生在导管或心房颤动消融术后和心房肌病患者中。左心房(LA)中的预先存在的瘢痕可导致复杂的回路,有时伴有狭窄的通道,可通过高分辨率映射检测到。LA 最常见的宏观折返性 AT 形式是二尖瓣环和房顶依赖性折返的变体。在纤维化的情况下发生局部折返性节律,导致传导缓慢,可能发生在先前消融区域的附近。治疗这些 AT 的方法包括首先确定左心房起源,定义心动过速回路 - 这可以通过超高密度映射和拖带来促进 - 并选择合适的峡部进行消融。消融左房扑动的一个重要终点是建立和确认双向阻滞线。消融这些 AT 的挑战包括存在多种心动过速、定义具有复杂激活模式的回路以及实现持久的阻滞线,特别是在外侧二尖瓣峡部。治疗这些心律失常的进展来自新的映射技术和对心外膜连接的认识,这些连接允许在消融病变之间持续传导。此外,输送能量以获得完全透壁病变的进展有望提高消融 LA 中 AT 的长期成功率。