Zhang Fei, Kong Fan-Dong, Ma Qing-Yun, Xie Qing-Yi, Zhou Li-Man, Zhao You-Xing, Guo Lei
Jiangsu Key Laboratory of Marine Bioresources and Environment, Co-innovation Center of Jiangsu Marine Bio-industry Technology, Jiangsu Ocean University, Lianyungang 222005, China.
Haina Key Laboratory of Research and Development of Natural Product from Li Folk Medicine, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China.
J Asian Nat Prod Res. 2020 Nov;22(11):999-1005. doi: 10.1080/10286020.2019.1670647. Epub 2019 Oct 3.
Seven compounds were isolated from a marine-derived fungus sp. ZF-79, including three new polyketides (-), named asperochrins D-F, along with four known compounds . Their structures were determined on the basis of spectroscopic methods. All the compounds were tested for quorum sensing inhibitory (QSI) activity. Compounds , , , and exhibited QSI activity against CV026 with MIC values of 50, 100, 50, 50, and 6.25 μM, respectively.
从一株海洋来源的真菌ZF-79中分离出7种化合物，其中包括3种新的聚酮化合物（-），命名为asperochrins D-F，以及4种已知化合物。它们的结构通过光谱方法确定。对所有化合物进行了群体感应抑制（QSI）活性测试。化合物、、、和对CV026表现出QSI活性，其MIC值分别为50、100、50、50和6.25μM。
