Retina and Uveitis Services, L V Prasad Eye Institute, Visakhapatnam, Andhra Pradesh, India.
Uveitis and Ocular Immunology Services, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Ocul Immunol Inflamm. 2021 Jan 2;29(1):102-106. doi: 10.1080/09273948.2019.1659830. Epub 2019 Oct 3.
: To describe full thickness miliary retinal lesions in ocular syphilis.: Retrospective chart review of patients with serologically confirmed ocular syphilis. Retinal miliary lesions in three cases of Syphilitic uveitis, in immunocompetent individuals are described. Case 1 and case 2 were positive for both VDRL (venereal disease research laboratory) and TPHA (Treponema pallidum hemagglutination), case 3 was VDRL negative but TPHA positive.: Miliary lesions were small round to oval, yellow retinal lesions, measuring less than ¼ disc diameter size, with distinct margins, involving complete thickness of retina on OCT, in a pillar like manner, associated with ground glass retinitis, outer retinal placoid lesion or with retinal vasculitis. In cases 1 and 3, these healed with pigmentation.: In contrast to similar lesions described, retinal miliary lesions seem to involve full thickness of the retina on OCT and may heal with pigmentation. These lesions may be characteristic of ocular syphilis.
描述眼部梅毒的全层粟粒状视网膜病变。
对经血清学证实患有眼部梅毒的患者进行回顾性图表审查。描述了 3 例免疫功能正常的梅毒性葡萄膜炎患者的视网膜粟粒状病变。病例 1 和病例 2 的 VDRL(性病研究实验室)和 TPHA(梅毒螺旋体血凝)均为阳性,病例 3 的 VDRL 为阴性但 TPHA 为阳性。
粟粒状病变为小而圆到椭圆形的黄色视网膜病变,直径小于四分之一视盘,边界清晰,OCT 显示累及视网膜全层,呈柱状,伴有玻璃样视网膜炎、视网膜外板块状病变或视网膜血管炎。在病例 1 和病例 3 中,这些病变通过色素沉着愈合。
与描述的类似病变不同,OCT 显示视网膜粟粒状病变似乎累及视网膜全层,可能通过色素沉着愈合。这些病变可能是眼部梅毒的特征。