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新型冠状病毒肺炎感染患者的视网膜表现:一项连续病例系列研究。

Retinal manifestations in patients following COVID-19 infection: A consecutive case series.

作者信息

Goyal Mallika, Murthy Somasheila I, Annum Sridhar

机构信息

Retina-Uveitis Service, Department of Ophthalmology, Apollo Health City, Hyderabad, Telangana, India.

Uveitis Service, L. V. Prasad Eye Institute, Hyderabad, Telangana, India.

出版信息

Indian J Ophthalmol. 2021 May;69(5):1275-1282. doi: 10.4103/ijo.IJO_403_21.

Abstract

PURPOSE

To describe retinal manifestations seen in patients associated with COVID-19 infection at a multi-specialty tertiary care hospital in Southern India.

METHODS

In this retrospective chart review, all consecutive cases presenting to the Retina-Uveitis service from May 2020 to January 2021 with retinal manifestations associated with COVID-19 infection or its sequelae or as a result of treatment given for COVID-19 were included.

RESULTS

: Of the 7 patients, 3 were female, and 4 were male. Four patients had onset of symptoms during the active phase of COVID-19 infection. Four had bilateral and three had unilateral involvement. The manifestations ranged from mild to vision threatening. Vision threatening manifestations included infections: endogenous endophthalmitis, candida retinitis and tubercular choroidal abscess and bilateral pre-foveal hemorrhages. Milder manifestations included paracentral acute middle maculopathy, central serous chorio-retinopathy and voriconazole induced visual symptoms. Final visual acuity was 6/36 or better in the four severe cases and 6/9 or better in the mild cases.

CONCLUSION

This study highlights the retinal manifestations associated with COVID-19 infection and its sequelae. As these patients presented with an association with COVID-19 (either during or after recovery), ophthalmologists should be vigilant and screen for such entities in case of complaints of visual symptoms or in the presence of systemic sepsis. The outcomes can be good with prompt and aggressive management.

摘要

目的

描述在印度南部一家多专科三级护理医院中与新型冠状病毒肺炎(COVID-19)感染相关患者的视网膜表现。

方法

在这项回顾性病历审查中,纳入了2020年5月至2021年1月期间连续就诊于视网膜-葡萄膜炎科、具有与COVID-19感染及其后遗症相关的视网膜表现或因COVID-19治疗所致视网膜表现的所有病例。

结果

7例患者中,3例为女性,4例为男性。4例患者在COVID-19感染的活动期出现症状。4例为双侧受累,3例为单侧受累。表现范围从轻度到威胁视力。威胁视力的表现包括感染:内源性眼内炎、念珠菌性视网膜病变和结核性脉络膜脓肿以及双侧黄斑中心凹前出血。较轻的表现包括旁中心急性中浆性黄斑病变、中心性浆液性脉络膜视网膜病变和伏立康唑引起的视觉症状。4例重症患者的最终视力为6/36或更好,轻症患者的最终视力为6/9或更好。

结论

本研究强调了与COVID-19感染及其后遗症相关的视网膜表现。由于这些患者表现出与COVID-19相关(在感染期间或恢复后),眼科医生应保持警惕,在患者出现视觉症状主诉或存在全身脓毒症时筛查此类病症。及时积极的治疗可取得良好的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/059b/8186578/3634288b43e1/IJO-69-1275-g001.jpg

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