State Key Laboratory of Hybrid Rice, Department of Plant Science, College of Life Sciences, Wuhan University , Wuhan , China.
Plant Signal Behav. 2019;14(11):1669418. doi: 10.1080/15592324.2019.1669418. Epub 2019 Oct 3.
Mutations in gene not only produce pleiotropic phenotypes of plant development but also impair plant adaptive responses under various stresses. However, the role of gene in sugar signaling is not known. In this study, we first found that deficiency significantly sensitized the sugar-induced anthocyanin accumulation and the sugar-inhibited primary root growth, suggesting BIG is an important component of the sugar signaling pathway. Then we found that mutant plants had higher sugar levels compared with the wild type, indicating the involvement of gene in regulating plant sugar homeostasis. Importantly, we also found that the relative ratio of carbon to nitrogen (C/N) was greatly enhanced by deficiency. Overall, our work expands the known functionality of BIG and reveals its role in regulating sugar response and C/N balance. It is likely that BIG connects nutrient, light, and hormone signaling networks for regulating plant development and adaptive responses.
基因中的突变不仅会导致植物发育的多种表型，还会损害植物在各种胁迫下的适应反应。然而，该基因在糖信号转导中的作用尚不清楚。在这项研究中，我们首先发现，基因缺失显著增强了糖诱导的花青素积累和糖抑制的主根生长，表明 BIG 是糖信号通路的一个重要组成部分。然后我们发现，与野生型相比，突变体植物的糖含量更高，这表明该基因参与了植物糖稳态的调节。重要的是，我们还发现基因缺失大大增强了碳氮比（C/N）。总的来说，我们的工作扩展了 BIG 的已知功能，并揭示了它在调节糖反应和 C/N 平衡中的作用。很可能 BIG 连接了营养、光照和激素信号网络，以调节植物的发育和适应反应。
