State Key Laboratory of Rice Biology and Key Lab of the Ministry of Agriculture for Nuclear Agricultural Sciences, Institute of Nuclear Agricultural Sciences, Zhejiang University, Hangzhou 310029, China.
Plant Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, NY 14853, USA.
Int J Mol Sci. 2020 Sep 26;21(19):7095. doi: 10.3390/ijms21197095.
Sugars, which are important signaling molecules, regulate diverse biological processes in plants. However, the convergent regulatory mechanisms governing these physiological activities have not been fully elucidated. MODIFIER OF snc1-1 (MOS1), a modulator of plant immunity, also regulates floral transition, cell cycle control, and other biological processes. However, there was no evidence of whether this protein was involved in sugar responses. In this study, we found that the loss-of-function mutant () was hypersensitive to sugar and was characterized by defective germination and shortened roots when grown on high-sugar medium. The expression of was enhanced by sucrose. , an important gene involved in sugar signaling, was upregulated in the mutant compared to wild-type Col-0 in response to sugar. Furthermore, the mutant accumulated more anthocyanin than did wild-type Col-0 when grown on high-sugar concentration medium or under high light. MOS1 was found to regulate the expression of flavonoid and anthocyanin biosynthetic genes in response to exogenous sucrose and high-light stress but with different underlying mechanisms, showing multiple functions in addition to immunity regulation in plant development. Our results suggest that the immune regulator MOS1 serves as a coordinator in the regulatory network, governing immunity and other physiological processes.
糖是重要的信号分子，调节植物中的多种生物过程。然而，调节这些生理活动的收敛调控机制尚未完全阐明。SNC1-1（SNC1-1）的调节剂（MOS1）是植物免疫的调节剂，也调节花发育、细胞周期控制和其他生物过程。然而，没有证据表明这种蛋白质是否参与糖反应。在这项研究中，我们发现功能丧失突变体（）对糖敏感，在高糖培养基上生长时表现出发芽缺陷和根缩短。蔗糖增强了的表达。与野生型 Col-0 相比，在响应糖时，参与糖信号的重要基因（）在突变体中上调。此外，当在高糖浓度培养基或高光下生长时，突变体积累的花青素多于野生型 Col-0。MOS1 被发现响应外源性蔗糖和高光胁迫调节类黄酮和花青素生物合成基因的表达，但具有不同的潜在机制，除了在植物发育中调节免疫外，还具有多种功能。我们的结果表明，免疫调节剂 MOS1 作为调控网络中的协调因子，调节免疫和其他生理过程。
