Smokovitis A, Wagner M, Starlinger M, Opitz A, Binder B R
Thromb Haemost. 1985 Feb 18;53(1):130-3.
A markedly decreased plasminogen activator activity (PAA) was seen in lung, heart and kidney after experimental hypovolemia in the pig. In 2 of 12 cases, an increased PAA was found in liver and spleen. In skeletal muscle, skin, sciatic nerve and in 10 of 12 cases in liver and spleen PAA was unchanged. A slightly increased plasmin inhibition was noted only in the lung. These changes in tissue PAA were reflected by an increase in the PAA of euglobulin fractions concomitant with a decrease in antiplasmin activity in the blood samples obtained during the bleeding experiments.
在猪实验性低血容量后,肺、心脏和肾脏中的纤溶酶原激活物活性(PAA)明显降低。在12例中的2例中,肝脏和脾脏中的PAA增加。在骨骼肌、皮肤、坐骨神经以及12例中的10例肝脏和脾脏中,PAA未发生变化。仅在肺中观察到纤溶抑制略有增加。这些组织PAA的变化反映在优球蛋白组分的PAA增加,同时在出血实验期间采集的血样中抗纤溶酶活性降低。