Strauss Sara B, Meng Alicia, Ebani Edward J, Chiang Gloria C
Department of Radiology, Weill Cornell Medical Center, 525 East 68th Street, Box 141, New York, NY 10065, USA.
Department of Radiology, Weill Cornell Medical Center, 525 East 68th Street, Box 141, New York, NY 10065, USA.
Radiol Clin North Am. 2019 Nov;57(6):1199-1216. doi: 10.1016/j.rcl.2019.07.003. Epub 2019 Aug 16.
Radiographic monitoring of posttreatment glioblastoma is important for clinical trials and determining next steps in management. Evaluation for tumor progression is confounded by the presence of treatment-related radiographic changes, making a definitive determination less straight-forward. The purpose of this article was to describe imaging tools available for assessing treatment response in glioblastoma, as well as to highlight the definitions, pathophysiology, and imaging features typical of true progression, pseudoprogression, pseudoresponse, and radiation necrosis.
胶质母细胞瘤治疗后的影像学监测对于临床试验和确定下一步治疗方案至关重要。由于存在与治疗相关的影像学改变，肿瘤进展的评估变得复杂，使得明确诊断不那么直接。本文的目的是描述可用于评估胶质母细胞瘤治疗反应的成像工具，并强调真正进展、假性进展、假性反应和放射性坏死的定义、病理生理学及典型的影像学特征。
