人类胸腺瘤中淋巴细胞的亚群
Subpopulations of lymphocytes in human thymomas.
作者信息
Lauriola L, Piantelli M, Carbone A, Dina M A, Scoppetta C, Musiani P
出版信息
Clin Exp Immunol. 1979 Sep;37(3):502-6.
Abstract
Lymphocyte populations in six normal thymuses and ten thymomas were examined. The majority of lymphocytes from both thymus and thymoma differ from peripheral T lymphocytes in their capacity to form E-rosettes resistant to incubation at 37 degrees C. Low percentages of T lymphocytes bearing receptors for the Fc portion of IgG (TG) and IgM (TM) were found in normal thymus. In contrast, lymphocytes from five out of nine thymomas showed remarkable percentages of TM cells. Compared with normal thymocytes, lymphocytes from seven out of ten thymomas responded vigorously to mitogens. The possible origin and nature of thymoma lymphocytes are discussed.
摘要
对六个正常胸腺和十个胸腺瘤中的淋巴细胞群体进行了检查。来自胸腺和胸腺瘤的大多数淋巴细胞在形成对37℃孵育有抗性的E花环的能力方面与外周T淋巴细胞不同。在正常胸腺中发现带有IgG（TG）和IgM（TM）Fc部分受体的T淋巴细胞百分比很低。相比之下，九个胸腺瘤中有五个的淋巴细胞显示出显著百分比的TM细胞。与正常胸腺细胞相比，十个胸腺瘤中有七个的淋巴细胞对有丝分裂原反应强烈。讨论了胸腺瘤淋巴细胞的可能起源和性质。
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