Bartoccioni E, Scuderi F, Scoppetta C, Evoli A, Tonali P, Guidi L, Bartoloni C, Terranova T
J Neurol. 1980;224(1):9-15. doi: 10.1007/BF00313202.
The antiacetylcholine receptor antibody was titered in the serum of 63 patients with myasthenia gravis (MG) and 20 control healthy subjects. The titer was significantly high in 92% of MG patients in contrast with none of the controls and no correlation was found with the thymus pathology and the severity of the disease. The titer decreased after thymectomy almost steadily with the improvement of the myasthenic signs. The role of the antibody in the pathogenesis of the disease is discussed.
对63例重症肌无力（MG）患者和20名健康对照者的血清进行抗乙酰胆碱受体抗体滴度检测。结果显示，92%的MG患者抗体滴度显著升高，而对照组无一例升高，且抗体滴度与胸腺病理及疾病严重程度无关。胸腺切除术后，随着肌无力症状的改善，抗体滴度几乎呈稳定下降趋势。本文还讨论了该抗体在疾病发病机制中的作用。
