Singh Rajiv, Choudhri Kishor, Sinha Saurabh, Mason Suzanne, Lecky Fiona, Dawson Jeremy
Health Services Research, School of Health and Related Research (ScHARR), Faculty of Medicine, Dentistry and Health, University of Sheffield, S1 4DA, UK; Osborn Neurorehabilitation Unit, Department of Rehabilitation Medicine, Sheffield Teaching Hospitals, Sheffield, S5 7AU, UK.
Department of Neurosurgery, Sheffield Teaching Hospitals, Glossop Road, Sheffield, S10 2JF, UK.
Clin Neurol Neurosurg. 2019 Nov;186:105526. doi: 10.1016/j.clineuro.2019.105526. Epub 2019 Sep 19.
Traumatic Brain Injury(TBI) is one of the most common neurosurgical emergencies but the long-term outcome remains unclear. This study investigated the global outcome and return to work after TBI and tried to identify any relationships that exist with injury and demographic features.
PATIENTS & METHODS: 1322 consecutive TBI admissions over 4 years, assessed at a specialist neurorehabilitation clinic at 10weeks and 1 yr. The outcomes were Extended Glasgow Outcome Scale(GOSE), return to work, Rivermead Head Injury Follow-up Questionnaire, Rivermead Post-Concussion Symptoms and the Hospital Anxiety and Depression Score.
1 year follow-up was achieved in 1207(91.3%). Mean age was 46.9(SD17.3) and 49.2% had mild TBI. The proportion attaining Good Recovery increased from 25.1% to 42.9% by 1 year. However 11.4% deteriorated in GOSE. Only 28.1% of individuals returned to the same pre-morbid level of work by 10 weeks, improving to 45.9% at 1 year. Over a quarter (25.6%) at 1 year were unable to make any return to work or study. Several demographic and injury variables were associated with these outcomes including TBI severity, social class, past psychiatric history and alcohol intoxication. These may allow targeting of vulnerable individuals.
In a largely representative TBI population including predominantly mild injury, there is still considerable functional disability at 1 year and many individuals are unable to make any return to pre-morbid vocation.
创伤性脑损伤(TBI)是最常见的神经外科急症之一,但其长期预后仍不明确。本研究调查了TBI后的整体预后和重返工作情况,并试图确定其与损伤及人口统计学特征之间存在的任何关系。
连续4年收治的1322例TBI患者,在一家专业神经康复诊所于10周和1年时进行评估。结局指标包括扩展格拉斯哥预后量表(GOSE)、重返工作情况、里弗米德头部损伤随访问卷、里弗米德脑震荡后症状以及医院焦虑抑郁量表评分。
1207例(91.3%)患者完成了1年随访。平均年龄为46.9岁(标准差17.3),49.2%为轻度TBI。到1年时,达到良好恢复的比例从25.1%增至42.9%。然而,11.4%的患者GOSE评分恶化。到10周时,只有28.1%的个体恢复到病前相同的工作水平,1年时这一比例提高到45.9%。1年时超过四分之一(25.6%)的患者无法重返工作或学习。包括TBI严重程度、社会阶层、既往精神病史和酒精中毒在内的几个人口统计学和损伤变量与这些结局相关。这些因素可能有助于确定易受影响的个体。
在一个以轻度损伤为主的具有广泛代表性的TBI人群中,1年时仍存在相当程度的功能残疾,许多个体无法重返病前职业。