Department of Basic and Applied Sciences, National Institute of Food Technology, Entrepreneurship and Management, Kundli, Sonepat, 131028, Haryana, India.
Department of Food Technology, JamiaHamdard University, New Delhi, 110062, India.
J Steroid Biochem Mol Biol. 2020 Feb;196:105489. doi: 10.1016/j.jsbmb.2019.105489. Epub 2019 Oct 2.
Today, as per the latest medical reports available, majority of the population throughout globe is facing vitamin D (Vit D) deficiency. Even in sub-tropical countries like India and many others Vit D deficiency is highly prevalent despite the exuberant available sunshine (a major source of Vit D) throughtout the year. The reason could be attributed to an array of factors including socioeconomical, cultural and religious. Further, other than the sunlight, there are very limited sources of Vit D to fulfil the recommended dietary allowance of Vit D (RDA: 400-800 IU per day). A large proportion of Vit D is lost during food processing and storage due to environmental stress conditions such as temperature, pH, salt, oxygen and light. Vita D, an important micronutrient, is essentially required for the prevention of disorders such as neurodegenerative diseases, cardiovascular diseases, cancer etc. in addition to its traditional role in bone metabolism. Therefore, in order to meet the daily requirements of Vit D for human body, WHO has recognized fortification as the most efficient and safest method to address malnutrition. But there are innumerable chellenges involved during food fortification using Vit D as fortificants such as homogeneity into the food matrix, physico-chemical/photochemical degradation, loss during processing and storage, interactions with other components of food matrix resulting into change in taste, texture and appearance thus affecting acceptability, palatability and marketability. Fortification of Vit D into food products especially the ones which have an aqueous portion, is not simple for food technologist. Recent advances in nanotechnology offer various microencapsulation techniques such as liposome, solid-lipid particles, nanostructured lipid carriers, emulsion, spray drying etc. which have been used to design efficient nanomaterials with desired functionality and have great potential for fortification of fortificants like Vit D. The present review is an undate on Vit D, in light of its fortification level, RDA, factors affecting its bioavailability and various microencapsulation techniques adopted to develop Vit D-nanomaterials and their fate in food fortification.
如今,根据最新的医学报告,全球大多数人都面临维生素 D(Vit D)缺乏的问题。即使在像印度这样的亚热带国家,尽管全年都有充足的阳光(Vit D 的主要来源),但 Vit D 缺乏的情况仍然非常普遍。原因可能是多方面的,包括社会经济、文化和宗教等因素。此外,除了阳光之外,能够满足维生素 D 推荐膳食摄入量(RDA:每天 400-800IU)的 Vit D 来源非常有限。由于温度、pH 值、盐、氧气和光线等环境压力条件,Vit D 在食品加工和储存过程中会大量流失。Vit D 作为一种重要的微量营养素,除了在骨骼代谢中的传统作用外,对于预防神经退行性疾病、心血管疾病、癌症等疾病也是必不可少的。因此,为了满足人体对 Vit D 的日常需求,世界卫生组织已将强化作为解决营养不良问题最有效和最安全的方法。但是,在使用 Vit D 作为强化剂进行食品强化时,存在着无数的挑战,例如均匀分布在食品基质中、物理化学/光化学降解、加工和储存过程中的损失、与食品基质其他成分的相互作用导致口感、质地和外观发生变化,从而影响可接受性、美味性和市场性。对于食品技术人员来说,将 Vit D 强化到食品产品中特别是那些含有水相的产品并不简单。纳米技术的最新进展提供了各种微胶囊化技术,如脂质体、固体脂质颗粒、纳米结构脂质载体、乳液、喷雾干燥等,这些技术已被用于设计具有所需功能的高效纳米材料,并为 Vit D 等强化剂的强化提供了巨大的潜力。本综述根据 Vit D 的强化水平、RDA、影响其生物利用度的因素以及用于开发 Vit D-纳米材料的各种微胶囊化技术及其在食品强化中的命运,提供了有关 Vit D 的最新信息。