INSERM, U1028, CNRS, UMR5292, Lyon Neuroscience Research Center, Psychiatric Disorders: from Resistance to Response Team, Lyon, F-69000, France; University Lyon 1, Villeurbanne, F-69000, France; Centre Hospitalier Le Vinatier, Bron, France.
Centre Hospitalier de la Côte Basque, F-64109, Bayonne, France.
Asian J Psychiatr. 2019 Dec;46:15-18. doi: 10.1016/j.ajp.2019.09.034. Epub 2019 Sep 27.
Most individuals with schizophrenia (SZ) have little to no insight regarding the presence of their illness. Psychoeducational programs are state-of-the-art interventions that consist in delivering stabilized patients with accurate knowledge about their illness and its treatment. Evidence suggests a significant relationship between levels of illness-related knowledge and insight in SZ patients. However, the effect of psychoeducation on these related outcomes needs to be explored further.
In this open label study involving 30 French-speaking patients with SZ, we propose to compare levels of knowledge and insight before and after the French P.A.C.T.® psychoeducation program to investigate how this approach affects both outcomes. Knowledge levels were measured with the self-questionnaire "What do I know?". Insight levels were measured using the Scale to Assess Unawareness of Mental Disorder (SUMD). Symptoms were assessed with the Positive And Negative Syndrome Scale (PANSS).
A large significant improvement of knowledge was observed (p < 0.001; d = 0.77). By contrast, the analysis reported no significant effect of psychoeducation on insight (p = 0.86; d = 0.07). PANSS total scores were significantly decreased after treatment (p = 0.001; d = 0.66).
Although the P.A.C.T.® program is a promising tool for improving illness-related knowledge in SZ patients, its use is not sufficient to significantly improve insight levels.
大多数精神分裂症(SZ)患者对自身疾病的存在几乎没有或完全没有认识。心理教育项目是一种最先进的干预措施,旨在向病情稳定的患者提供关于其疾病及其治疗的准确知识。有证据表明,SZ 患者的疾病相关知识水平与洞察力之间存在显著关系。然而,心理教育对这些相关结果的影响需要进一步探讨。
在这项涉及 30 名法语 SZ 患者的开放性标签研究中,我们拟比较法国 P.A.C.T.®心理教育项目前后的知识和洞察力水平,以研究这种方法如何影响这两个结果。知识水平通过自我问卷“我知道什么?”来衡量。洞察力水平通过使用精神疾病意识缺失量表(SUMD)来衡量。症状通过阳性和阴性综合征量表(PANSS)进行评估。
观察到知识水平显著提高(p<0.001;d=0.77)。相比之下,分析报告表明心理教育对洞察力没有显著影响(p=0.86;d=0.07)。治疗后 PANSS 总分显著下降(p=0.001;d=0.66)。
尽管 P.A.C.T.® 项目是改善 SZ 患者疾病相关知识的有前途的工具,但它的使用不足以显著提高洞察力水平。