亨廷顿舞蹈病中壳核的神经元分布
Neuronal distribution in the putamen in Huntington's disease.
作者信息
Roos R A, Pruyt J F, de Vries J, Bots G T
出版信息
J Neurol Neurosurg Psychiatry. 1985 May;48(5):422-5. doi: 10.1136/jnnp.48.5.422.
Abstract
The numbers of neurons were counted in the ventral and dorsal anterior and ventral and dorsal posterior part of the putamen of 11 Huntington's disease and nine control patients. The process of neuronal cell loss in Huntington's disease proved to be unevenly spread throughout the putamen; the ventral anterior part was relatively spared as compared with the other parts of the putamen. A significantly higher number of neurons was found in the ventral part of the putamen in the controls.
摘要
对11例亨廷顿舞蹈症患者和9例对照患者壳核的腹侧和背侧前部以及腹侧和背侧后部的神经元数量进行了计数。结果表明，亨廷顿舞蹈症患者的神经元细胞丢失过程在整个壳核中分布不均；与壳核的其他部分相比，腹侧前部相对未受影响。在对照组中，壳核腹侧的神经元数量明显更多。
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