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本文引用的文献

1
Modeled exposure to tetrachloroethylene-contaminated drinking water and the risk of placenta-related stillbirths: a case-control study from Massachusetts and Rhode Island.建模接触四氯乙烯污染饮用水与胎盘相关死胎风险：来自马萨诸塞州和罗得岛的病例对照研究。
Environ Health. 2018 Jul 3;17(1):58. doi: 10.1186/s12940-018-0402-1.
2
Residential Proximity to Major Roadways and Risk of Incident Ischemic Stroke in NOMAS (The Northern Manhattan Study).居民与主要道路的距离与 NOMAS（北部曼哈顿研究）中首发缺血性脑卒中的风险
Stroke. 2018 Apr;49(4):835-841. doi: 10.1161/STROKEAHA.117.019580. Epub 2018 Mar 14.
3
Risk factors in cardiovascular disease mortality associated with high exposure to vehicular traffic.与高暴露于车辆交通相关的心血管疾病死亡风险因素。
Rev Bras Epidemiol. 2017 Jul-Sep;20(3):423-434. doi: 10.1590/1980-5497201700030006.
4
Residential Proximity to Roadways and Ischemic Placental Disease in a Cape Cod Family Health Study.科德角家庭健康研究中住宅与道路的距离及缺血性胎盘疾病
Int J Environ Res Public Health. 2017 Jun 24;14(7):682. doi: 10.3390/ijerph14070682.
5
Short-Term Exposure to Urban Air Pollution and Influences on Placental Vascularization Indexes.短期暴露于城市空气污染及其对胎盘血管生成指数的影响。
Environ Health Perspect. 2017 Apr;125(4):753-759. doi: 10.1289/EHP300. Epub 2016 Jul 6.
6
Prenatal ambient air pollution exposure and the risk of stillbirth: systematic review and meta-analysis of the empirical evidence.产前暴露于环境空气污染与死产风险：实证证据的系统评价和荟萃分析
Occup Environ Med. 2016 Sep;73(9):573-81. doi: 10.1136/oemed-2015-103086. Epub 2016 May 24.
7
Stillbirths: rates, risk factors, and acceleration towards 2030.死产：发生率、风险因素及 2030 年目标进展
Lancet. 2016 Feb 6;387(10018):587-603. doi: 10.1016/S0140-6736(15)00837-5. Epub 2016 Jan 19.
8
Exposure to airborne particulate matter during pregnancy is associated with preterm birth: a population-based cohort study.孕期暴露于空气中的颗粒物与早产有关：一项基于人群的队列研究。
Environ Health. 2016 Jan 15;15:6. doi: 10.1186/s12940-016-0094-3.
9
Exploring the intangible economic costs of stillbirth.探究死产的无形经济成本。
BMC Pregnancy Childbirth. 2015 Sep 1;15:188. doi: 10.1186/s12884-015-0617-x.
10
Maternal ambient air pollution exposure preconception and during early gestation and offspring congenital orofacial defects.孕期及孕早期孕妇暴露于环境空气污染与子代先天性口面部缺陷
Environ Res. 2015 Jul;140:714-20. doi: 10.1016/j.envres.2015.06.002. Epub 2015 Jun 20.

居住地点与道路的距离和胎盘相关死产：一项病例对照研究。

Residential proximity to roadways and placental-associated stillbirth: a case-control study.

作者信息

Butler Lindsey, Gallagher Lisa, Winter Michael, Fabian M Patricia, Wesselink Amelia, Aschengrau Ann

机构信息

Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA.

Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.

出版信息

Int J Environ Health Res. 2021 Jun;31(4):465-474. doi: 10.1080/09603123.2019.1673882. Epub 2019 Oct 6.

DOI:10.1080/09603123.2019.1673882
PMID:31587563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7131873/
Abstract

We conducted a retrospective case-control study of 1,097 women in Massachusetts and Rhode Island, USA, to examine the association between stillbirth related to placental abruption or placental insufficiency and maternal exposure to traffic-related air pollution. We utilized distance to nearest roadway proximity metrics as a proxy for traffic-related air pollution exposure. No meaningful increase in the overall odds of placental-associated stillbirths was observed (adjusted OR: 1.1, 95% CI: 0.5-2.8). However, mothers living within 50 m of a roadway had a 60% increased odds of experiencing a stillbirth related to placental abruption compared to mothers living greater than 200 m away. This suggestive finding was imprecise due to the small case number in the highest exposure category (95% CI: 0.6-4.0). Future studies of placental abruption with more precise exposure assessments are warranted.

摘要

我们对美国马萨诸塞州和罗德岛的1097名女性进行了一项回顾性病例对照研究，以检验与胎盘早剥或胎盘功能不全相关的死产与母亲暴露于交通相关空气污染之间的关联。我们使用到最近道路的距离指标作为交通相关空气污染暴露的替代指标。未观察到与胎盘相关死产的总体几率有显著增加（调整后的比值比：1.1，95%置信区间：0.5-2.8）。然而，与居住在距离道路200米以上的母亲相比，居住在距离道路50米以内的母亲经历与胎盘早剥相关死产的几率增加了60%。由于最高暴露类别中的病例数较少，这一提示性发现并不精确（95%置信区间：0.6-4.0）。有必要对胎盘早剥进行更精确暴露评估的未来研究。