Nihon Shokuhin Kako Co., Ltd., 30 Tajima, Fuji, 417-8530, Japan.
Nihon Shokuhin Kako Co., Ltd., 30 Tajima, Fuji, 417-8530, Japan.
Carbohydr Res. 2019 Dec 1;486:107826. doi: 10.1016/j.carres.2019.107826. Epub 2019 Sep 26.
An efficient and environmentally friendly system for producing 5-hydroxymethylfurfural (5-HMF) from fructose has been proposed. Substrate concentration is an important factor for practical application of the process; however, use of a high concentration of fructose has rarely been tested in the reaction because the conditions accelerate intermolecular side reactions to form adhesive humins. Humin byproducts stuck on reactor surfaces can make the production of 5-HMF on an industrial scale difficult. Therefore, developing a catalytic reaction system that can promote the synthesis of 5-HMF from highly concentrated fructose without causing adhesion of humins to reactors is needed. The present study demonstrated that activated carbons are promising materials for this system. Activated carbon catalyzed the conversion of fructose to 5-HMF without adhesion of humins to reactor vessels under practical conditions of high substrate concentration up to 73.2%. The catalytic activity was determined not only by the amount of surface weakly acidic oxygenated groups but also by the adsorption of fructose. In addition, strong adsorption of 5-HMF led to low selectivity of 5-HMF and the formation of adhesive humins. This is the first report to describe the synthesis of 5-HMF from solutions containing a fructose concentration greater than 70%.
已提出一种从果糖高效且环保地生产 5-羟甲基糠醛（5-HMF）的方法。底物浓度是该过程实际应用的重要因素；然而，由于反应条件会加速形成粘性胡敏素的分子间副反应，因此很少在反应中测试果糖的高浓度使用。胡敏素副产物粘在反应器表面会使得在工业规模上生产 5-HMF 变得困难。因此，需要开发一种催化反应体系，能够在不导致胡敏素附着在反应器上的情况下，促进高浓度果糖合成 5-HMF。本研究表明，活性炭是该体系有前景的材料。在高达 73.2%的高底物浓度的实际条件下，活性炭在没有胡敏素附着到反应器容器的情况下催化果糖转化为 5-HMF。催化活性不仅取决于表面弱酸性含氧基团的数量，还取决于果糖的吸附。此外，5-HMF 的强烈吸附导致 5-HMF 的选择性低和粘性胡敏素的形成。这是第一篇描述从浓度大于 70%的果糖溶液中合成 5-HMF 的报告。
