Department of Chemistry, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang (KMITL), Bangkok, 10520, Thailand.
Department of Chemistry, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang (KMITL), Bangkok, 10520, Thailand; Advanced Materials Research Unit, Faculty of Science, King Mongkut's Institute of Technology Ladkrabang (KMITL), Bangkok, 10520, Thailand.
Carbohydr Polym. 2020 Jan 1;227:115360. doi: 10.1016/j.carbpol.2019.115360. Epub 2019 Sep 23.
Some applications, in particular, wound dressings, require significant water holding capability: hydrogels formed from Basil seed mucilage (BSM) are non-toxic natural substances and exhibit the needed water holding capacity. However, the sponges have low dimensional stability and easily degrade in aqueous media. We overcame this drawback by crosslinking with borax. To provide antibacterial activity, zinc oxide nanoparticles (ZnO-NP) were added. With 10-20 wt% added borax and ZnO-NP, all key properties improved: dimensional stability, water retention capacity (31 to 41%), stress at maximum load (2.6 to 6.6 MPa), Young's modulus (74 to 113 MPa) and strain (28 to 54%). An interconnecting system of pores with well distributed ZnO-NP was observed from scanning electron microscope. In addition, higher borax and ZnO-NP loadings slightly decreased porosity (92% to 73%) and swelling (109 to 56). Moreover, antibacterial activity and cytotoxicity of BSM hydrogel sponge were also examined.
某些应用，特别是伤口敷料，需要有很强的持水能力：由罗勒籽胶（BSM）形成的水凝胶是无毒的天然物质，具有所需的持水能力。然而，这些海绵的尺寸稳定性低，容易在水介质中降解。我们通过与硼砂交联克服了这一缺点。为了提供抗菌活性，添加了氧化锌纳米粒子（ZnO-NP）。加入 10-20wt%的硼砂和 ZnO-NP 后，所有关键性能都得到了改善：尺寸稳定性、保水能力（31%至 41%）、最大负载下的应力（2.6 至 6.6MPa）、杨氏模量（74 至 113MPa）和应变（28%至 54%）。从扫描电子显微镜观察到具有均匀分布 ZnO-NP 的互联孔系统。此外，较高的硼砂和 ZnO-NP 负载略微降低了孔隙率（92%至 73%）和溶胀（109%至 56%）。此外，还研究了 BSM 水凝胶海绵的抗菌活性和细胞毒性。
