Department of Production Animal Health, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3, Canada.
Department of Production Animal Health, University of Calgary Faculty of Veterinary Medicine, 11877 85th Street NW, Calgary, Alberta T3R 1J3, Canada.
Vet Clin North Am Food Anim Pract. 2019 Nov;35(3):557-573. doi: 10.1016/j.cvfa.2019.07.004.
A growing body of evidence has shown that calves can mount an immune response when vaccinated in the face of maternal antibodies (IFOMA), albeit inconsistently and often in ways that differ from seronegative calves or older cattle. Several previous reviews have endeavored to explain bovine neonatal immunology and have documented the issue of vaccinating young calves. However, as preweaning vaccination becomes more common in both beef and dairy production systems, so too has research on the impacts of such vaccination programs. This article aims to briefly review the challenges and opportunities for vaccinating calves IFOMA.
越来越多的证据表明，犊牛在面对母源抗体（IFOMA）时可以产生免疫反应，尽管这种反应不一致，而且通常与血清阴性犊牛或成年牛不同。之前有几项综述试图解释牛的新生儿免疫学，并记录了给小牛接种疫苗的问题。然而，随着犊牛在肉牛和奶牛生产系统中的免疫接种越来越普遍，对这些疫苗接种计划的影响的研究也越来越多。本文旨在简要回顾 IFOMA 犊牛免疫接种的挑战和机遇。
