Lazurko Madelana M, Erickson Nathan E N, Campbell John R, Gow Sheryl, Waldner Cheryl L
Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Public Health Agency of Canada, Saskatoon, SK, Canada.
Front Vet Sci. 2023 Aug 9;10:1235942. doi: 10.3389/fvets.2023.1235942. eCollection 2023.
Vaccinations are one of the most impactful tools available to cow-calf producers to control within herd disease and later, in feedlots. While vaccine use has been studied across Canada, inconsistent and variable regional data makes analysis and interpretation difficult. The objective of this study was to describe vaccination protocols and factors associated with vaccine use in Canadian cow-calf herds and define associations between vaccine use and productivity outcomes. Surveys describing vaccine use in 2020 were collected from 131 cow-calf herds (40 eastern, 91 western), recruited through a national beef cattle surveillance program. Ninety-two percent of cows and replacement heifers, and 72% of bulls were vaccinated with Infectious Bovine Rhinotracheitis (IBR), Bovine Viral Diarrhea Virus (BVDV), Parainfluenza3 Virus (PI3), and Bovine Respiratory Syncytial Virus (BRSV). At least half of cows and bulls were vaccinated for clostridial pathogens and cows and heifers for viral calf scours. Clostridial vaccines were significantly more likely to be used in western Canada compared to eastern Canada. While 92% of producers vaccinated suckling calves against IBR/BRSV/PI3, only 47% provided a second vaccine prior to weaning; 78% of calves were also vaccinated at least once for BVDV before weaning. Producers who vaccinated calves against IBR/BRSV/PI3 before 3 months of age provided a second dose prior to weaning more often than producers who administer the first IBR/BRSV/PI3 vaccine later. Vaccine use has increased across Canada, particularly in calves, prior to weaning. Relative to label recommendations for annual vaccination, clostridial vaccines were generally underutilized in cows and bulls, and by producers in eastern Canada as compared to western Canada. Opportunities also exist to improve adherence to label recommendations for the booster dose of scours vaccine when used in bred replacement heifers. Protocols including product choices, the timing and boosting of respiratory vaccines in nursing calves vary widely across herds. Use of intranasal vaccines in neonatal calves less than 2 weeks old has increased in western Canada compared to previous reports. There is a need to better understand how timing of vaccination in nursing calves contributes to effectiveness, for respiratory disease in nursing and weaned calves.
疫苗接种是肉牛养殖户控制牛群疾病(以及后续育肥阶段疾病)最有效的手段之一。虽然加拿大各地都对疫苗使用情况进行了研究,但区域数据不一致且变化较大,这使得分析和解读变得困难。本研究的目的是描述加拿大肉牛群的疫苗接种方案及与疫苗使用相关的因素,并确定疫苗使用与生产性能结果之间的关联。通过一项全国肉牛监测计划,从131个肉牛群(40个东部牛群、91个西部牛群)收集了描述2020年疫苗使用情况的调查数据。92%的母牛和后备小母牛以及72%的公牛接种了传染性牛鼻气管炎(IBR)、牛病毒性腹泻病毒(BVDV)、副流感3型病毒(PI3)和牛呼吸道合胞病毒(BRSV)疫苗。至少一半的母牛和公牛接种了针对梭菌病原体的疫苗,母牛和小母牛接种了预防病毒性犊牛腹泻的疫苗。与加拿大东部相比,加拿大西部使用梭菌疫苗的可能性显著更高。虽然92%的养殖户给哺乳犊牛接种了IBR/BRSV/PI3疫苗,但只有47%的养殖户在断奶前提供了第二次疫苗接种;78%的犊牛在断奶前也至少接种了一次BVDV疫苗。在3月龄前给犊牛接种IBR/BRSV/PI3疫苗的养殖户,比在更晚时候接种第一剂IBR/BRSV/PI3疫苗的养殖户,在断奶前更常提供第二剂疫苗。在加拿大,尤其是在犊牛断奶前,疫苗使用有所增加。相对于每年疫苗接种的标签建议,梭菌疫苗在母牛和公牛中普遍使用不足,而且与加拿大西部相比,加拿大东部的养殖户使用情况更差。在用于配种的后备小母牛中使用腹泻疫苗时,也存在提高对加强剂量标签建议依从性的机会。不同牛群之间,包括产品选择、哺乳犊牛呼吸道疫苗接种时间和加强接种等方案差异很大。与之前的报告相比,加拿大西部小于2周龄新生犊牛使用鼻内疫苗的情况有所增加。有必要更好地了解哺乳犊牛的疫苗接种时间如何影响疫苗效力,以及对哺乳和断奶犊牛呼吸道疾病的影响。