• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

阴囊探查术后睾丸癌的新辅助化疗:一例报告

Neo Adjuvant Chemotherapy on Testicular Cancer after Scrotal Exploration: A Case Report.

作者信息

Novianda Andhika H, Prapiska Fauriski Febrian

机构信息

Department of Urology, Faculty of Medicine, Universitas Indonesia, H. Adam Malik Hospital, Medan, Indonesia.

出版信息

Open Access Maced J Med Sci. 2019 Jul 13;7(14):2305-2308. doi: 10.3889/oamjms.2019.604. eCollection 2019 Jul 30.

DOI:10.3889/oamjms.2019.604
PMID:31592278
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6765077/
Abstract

BACKGROUND

A case of testicular cancer treated with neo adjuvant therapy in a patient in male is rare. When testicular cancer presents, it is usually directly operated due to the size of cancer which presented within the order of operable size.

CASE PRESENTATION

Here, we report a rare case of a 5-year-old male patient presented to the emergency room (ER) due to mass on the scrotum without the difficulty of urination. From clinical findings, mass with a size of 15 x 10 cm was found with multiple abscesses on both sides of the scrotum. Pathological Anatomy Examination confirmed yolk sac tumour present within the scrotal mass. Initially, palliative chemotherapy took place to reduce the growth rate of the tumour. However, due to the responsiveness of testicular cancer to chemotherapy drugs, it reduced into operable size testicular cancer. Wide excision and Orchidectomy was then performed, followed by adjuvant chemotherapy.

CONCLUSION

This case report showed the possibility of using neo adjuvant chemotherapy as an alternative treatment when inoperable testicular cancer presented in hospital.

摘要

背景

男性患者采用新辅助治疗的睾丸癌病例罕见。睾丸癌出现时,通常因癌肿大小处于可手术范围而直接进行手术。

病例报告

在此,我们报告一例罕见病例,一名5岁男性患者因阴囊肿物就诊于急诊室,无排尿困难。根据临床检查结果,发现一个大小为15×10厘米的肿物,阴囊两侧有多个脓肿。病理解剖检查证实阴囊肿物内存在卵黄囊瘤。最初进行了姑息化疗以降低肿瘤的生长速度。然而,由于睾丸癌对化疗药物有反应,肿瘤缩小到可手术大小的睾丸癌。随后进行了广泛切除和睾丸切除术,接着进行辅助化疗。

结论

本病例报告表明,当医院出现无法手术的睾丸癌时,使用新辅助化疗作为替代治疗方法是有可能的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/8f288b0c203b/OAMJMS-7-2305-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/6fd06fe23a35/OAMJMS-7-2305-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/e7223f5903d3/OAMJMS-7-2305-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/141a2d512619/OAMJMS-7-2305-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/65ff36286cbd/OAMJMS-7-2305-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/bb603ec5e70a/OAMJMS-7-2305-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/5814bc071e66/OAMJMS-7-2305-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/8dd8c8a850cf/OAMJMS-7-2305-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/8f288b0c203b/OAMJMS-7-2305-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/6fd06fe23a35/OAMJMS-7-2305-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/e7223f5903d3/OAMJMS-7-2305-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/141a2d512619/OAMJMS-7-2305-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/65ff36286cbd/OAMJMS-7-2305-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/bb603ec5e70a/OAMJMS-7-2305-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/5814bc071e66/OAMJMS-7-2305-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/8dd8c8a850cf/OAMJMS-7-2305-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5fef/6765077/8f288b0c203b/OAMJMS-7-2305-g008.jpg

相似文献

1
Neo Adjuvant Chemotherapy on Testicular Cancer after Scrotal Exploration: A Case Report.阴囊探查术后睾丸癌的新辅助化疗:一例报告
Open Access Maced J Med Sci. 2019 Jul 13;7(14):2305-2308. doi: 10.3889/oamjms.2019.604. eCollection 2019 Jul 30.
2
Testicular cancer at Kenyatta National Hospital, Nairobi.内罗毕肯雅塔国家医院的睾丸癌
East Afr Med J. 2000 Feb;77(2):80-5. doi: 10.4314/eamj.v77i2.46402.
3
Fungating scrotal mass: A rare clinical presentation of testicular tumor.阴囊蕈样肿块:睾丸肿瘤的一种罕见临床表现。
Indian J Urol. 2008 Jul;24(3):406-7. doi: 10.4103/0970-1591.42627.
4
Subcutaneous leiomyosarcoma of the scrotum mimickering testicular cancer. A case report and literature review.阴囊皮下平滑肌肉瘤误诊为睾丸癌。一例病例报告及文献复习。
Urol Case Rep. 2020 Nov 13;34:101487. doi: 10.1016/j.eucr.2020.101487. eCollection 2021 Jan.
5
A Rare Case of Ipsilateral Scrotal Recurrence of Testicular Cancer After Radical Orchidectomy.根治性睾丸切除术后同侧阴囊复发性睾丸癌1例罕见病例
Cureus. 2023 Dec 28;15(12):e51219. doi: 10.7759/cureus.51219. eCollection 2023 Dec.
6
Outcomes of scrotal exploration for acute scrotal pain suspicious of testicular torsion: a consecutive case series of 173 patients.阴囊探查术治疗疑似睾丸扭转的急性阴囊痛的结果:173 例连续病例系列。
BJU Int. 2011 Mar;107(6):990-3. doi: 10.1111/j.1464-410X.2010.09557.x. Epub 2010 Sep 21.
7
The acute scrotum: aetiology, management and early outcome-preliminary report.急性阴囊:病因、处理及早期转归——初步报告
Niger J Med. 2005 Jul-Sep;14(3):267-71.
8
Scrotal exploration for acute scrotal pain: a 10-year experience in two tertiary referral paediatric units.急性阴囊疼痛的阴囊探查:两家三级转诊儿科单位的10年经验
Scand J Urol. 2013 Oct;47(5):418-22. doi: 10.3109/00365599.2012.752403. Epub 2013 Jan 3.
9
Re-presentations and recurrent events following initial management of the acute paediatric scrotum: a 5-year review.小儿急性阴囊初次处理后的再表现及复发事件:一项5年回顾
ANZ J Surg. 2019 Apr;89(4):E117-E121. doi: 10.1111/ans.13905. Epub 2017 Feb 27.
10
Scrotal Involvement with Testicular Nonseminomatous Germ Cell Tumour.阴囊受累于睾丸非精原细胞性生殖细胞肿瘤。
Case Rep Oncol Med. 2016;2016:5471862. doi: 10.1155/2016/5471862. Epub 2016 Oct 17.

本文引用的文献

1
Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer.化疗诱导恶性睾丸生殖细胞瘤小鼠模型中 OCT4 阳性肿瘤干细胞耗竭
Cell Rep. 2017 Nov 14;21(7):1896-1909. doi: 10.1016/j.celrep.2017.10.078.
2
SEOM clinical guidelines for diagnosis and treatment of testicular seminoma (2010).SEOM 临床指南:睾丸精原细胞瘤的诊断和治疗(2010 年)。
Clin Transl Oncol. 2011 Aug;13(8):560-4. doi: 10.1007/s12094-011-0697-7.
3
EAU guidelines on testicular cancer: 2011 update.EAU 睾丸癌指南:2011 年更新版。
Eur Urol. 2011 Aug;60(2):304-19. doi: 10.1016/j.eururo.2011.05.038. Epub 2011 May 25.
4
Testicular germ cell tumors: pathogenesis, diagnosis and treatment.睾丸生殖细胞肿瘤:发病机制、诊断与治疗。
Nat Rev Endocrinol. 2011 Jan;7(1):43-53. doi: 10.1038/nrendo.2010.196. Epub 2010 Nov 30.
5
Cryptorchidism and testicular cancer: separating fact from fiction.隐睾症与睾丸癌:分清事实与虚构
J Urol. 2009 Feb;181(2):452-61. doi: 10.1016/j.juro.2008.10.074. Epub 2008 Dec 13.
6
Recent developments in germ cell tumors of the testes.睾丸生殖细胞肿瘤的最新进展
Curr Opin Oncol. 2008 May;20(3):287-93. doi: 10.1097/CCO.0b013e3282f8b064.
7
Epidemiological and clinical behavior of prepubertal testicular tumors in Korea.韩国青春期前睾丸肿瘤的流行病学及临床特征
J Urol. 2004 Aug;172(2):674-8. doi: 10.1097/01.ju.0000129571.13955.6b.
8
[Acute scrotum secondary to testicular tumor].睾丸肿瘤继发急性阴囊
Arch Esp Urol. 2002 Jan-Feb;55(1):71-3.
9
[Acute scrotum as clinical presentation form of testicular tumor].[急性阴囊作为睾丸肿瘤的临床表现形式]
Actas Urol Esp. 1993 Sep;17(8):501-2.
10
Delayed presentation of testicular tumors.睾丸肿瘤的延迟就诊
South Med J. 1980 Jan;73(1):33-5. doi: 10.1097/00007611-198001000-00013.