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成年人身体活动强度与心脏自主神经调节各领域之间的关系:一项观察性方案研究。

The relationship between physical activity intensity and domains with cardiac autonomic modulation in adults: An observational protocol study.

作者信息

Tebar William R, Ritti-Dias Raphael M, Saraiva Bruna T C, Gil Fernanda C S, Delfino Leandro D, Damato Tatiana M M, Aguilar Beatriz A S, Silva Stéfany C B, Mota Jorge, Vanderlei Luiz Carlos M, Christofaro Diego G D

机构信息

São Paulo State University (UNESP), School of Technology and Sciences, Presidente Prudente.

Universidade Nove de Julho (UNINOVE), Sao Paulo, Brazil.

出版信息

Medicine (Baltimore). 2019 Oct;98(41):e17400. doi: 10.1097/MD.0000000000017400.

Abstract

INTRODUCTION

Cardiac autonomic modulation is an important marker of cardiovascular health and the practice of physical activity is a fundamental tool for good maintenance or increments in this marker. However, it is not clear in the literature whether different intensities and different domains of physical activity are related in the same way to cardiac autonomic modulation.

OBJECTIVES

This randomized epidemiologic study will examine the relationship between cardiac autonomic modulation and different intensities and domains of physical activity in a representative sample of adults.

METHODS

The sample of study will consist of 252 subjects aged from 18 years and above. The sample will be randomized through census sectors in which the neighborhoods, streets, and houses will also be randomized. Cardiac autonomic modulation will be assessed by heart rate variability and the intensity (mild, moderate, intense) of physical activity will be evaluated by means of accelerometers, while the different domains of physical activity (physical activity at work, occupational activities) will be evaluated through a questionnaire. The relationship between cardiac autonomic modulation and different physical activity intensities, as well as the different domains will be analyzed by linear regression, considering a statistical significance of 5% and a 95% confidence interval. This research protocol is registered in ClinicalTrials.gov at number NCT03986879.

摘要

引言

心脏自主神经调节是心血管健康的重要指标,而体育活动是维持或提高这一指标的基本手段。然而,文献中尚不清楚不同强度和不同领域的体育活动与心脏自主神经调节的关系是否相同。

目的

这项随机流行病学研究将在具有代表性的成年样本中,研究心脏自主神经调节与不同强度和不同领域体育活动之间的关系。

方法

研究样本将包括252名18岁及以上的受试者。样本将通过普查区域进行随机分组,其中邻里、街道和房屋也将被随机化。心脏自主神经调节将通过心率变异性进行评估,体育活动强度(轻度、中度、剧烈)将通过加速度计进行评估,而体育活动的不同领域(工作中的体育活动、职业活动)将通过问卷调查进行评估。心脏自主神经调节与不同体育活动强度以及不同领域之间的关系将通过线性回归进行分析,显著性水平为5%,置信区间为95%。本研究方案已在ClinicalTrials.gov上注册,注册号为NCT03986879。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/059d/6799861/9f3dd1efe7df/medi-98-e17400-g003.jpg

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