分子进化：RNA 剪接机制兼职垃圾清除。

Molecular Evolution: RNA Splicing Machinery Moonlights in Junk Removal.

机构信息

Department of Biology, San Francisco State University, San Francisco, CA 94132, USA; Molecular Cell Biology, University of California-Merced, Merced, CA 95343, USA.

Molecular Cell Biology, University of California-Merced, Merced, CA 95343, USA.

出版信息

Curr Biol. 2019 Oct 7;29(19):R920-R922. doi: 10.1016/j.cub.2019.08.046.

DOI:10.1016/j.cub.2019.08.046

PMID:31593665

Abstract

A close relative of vertebrates solves the problem of gene-disrupting transposable element insertions by splicing them out at the RNA level. Why is such an elegant solution so rare across eukaryotes?

摘要

脊椎动物的近亲通过在 RNA 水平上剪接来解决基因破坏转座元件插入的问题。为什么这种优雅的解决方案在真核生物中如此罕见？