Electrochemical synthesis of carbon nano spheres and its application for detection of ciprofloxacin.

Carbon nano spheres (CNSs) were synthesized by single step electrochemical synthesis route in ultra-pure water as a medium of synthesis. Characterization of synthesized CNSs was carried out using atomic force microscope (AFM), particle size analyzer, zeta potential analyzer and Fourier Transform Infrared (FTIR) measurements, from which the information about the morphology and functional groups present on the surface of the particles are obtained. The particle size of the CNSs was found to be 6 nm. FTIR spectrum shows the presence of functional groups such as -OH, C≡C, C = C and on the CNSs. Electrochemical and spectroscopic experiments were conducted to determine the interaction of the drug molecule ciprofloxacin (Cf) with CNSs, strong interaction between Cf and CNSs leads to the development of analytical method of detection of Cf using CNSs as the pre-concentrating agent. The detection of limit of the present method is obtained as 0.15 μM at (S/N) ratio of 3. CNSs can be considered as a potential candidate for the fabrication of sensor for high sensitive determination of Cf.