Starcher B, Percival S
Connect Tissue Res. 1985;13(3):207-15. doi: 10.3109/03008208509152400.
During pregnancy the rat uterus shows a steady increase in total elastin content, reaching levels of 300% above non-pregnant controls. Elevated levels of urinary desmosine are also seen during this period. After parturition there is a slight lag period and then rapid removal of elastin from the uterus, reaching baseline after five days. Urinary desmosine levels were elevated for about seven days post partum before returning toward control levels. Analysis of pre- and post-partum serum showed no significant differences. The involuting rat uterus appears to be an excellent model for the study of processes involved in elastin catabolism.
在怀孕期间,大鼠子宫的总弹性蛋白含量稳步增加,达到比未怀孕对照组高300%的水平。在此期间,尿中异锁链素含量也会升高。分娩后有一个短暂的滞后期,然后弹性蛋白从子宫中迅速清除,五天后达到基线水平。产后约七天内,尿中异锁链素水平一直升高,之后才恢复到对照水平。对产前和产后血清的分析显示无显著差异。 involuting rat uterus似乎是研究弹性蛋白分解代谢相关过程的一个优秀模型。 (注:原文中“involuting rat uterus”直接保留英文未翻译,可能是专业术语,若有准确中文表述请根据实际情况替换。)