State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China.
J Mater Chem B. 2019 Nov 14;7(42):6469-6475. doi: 10.1039/c9tb01823a. Epub 2019 Oct 9.
Ratiometric electrochemiluminescence (ECL) assays have been widely applied in biosensing because of eliminated outside interferences and improved reliability in detection. In order to construct ratiometric ECL biosensors with high sensitivity and reliability, it is critical to find two signal emitters with suitable applied potentials or emission wavelengths. This review aims to discuss recent advances and trends of ratiometric ECL biosensors in terms of ECL materials and corresponding ratiometric sensing approaches. We focus on four types of ratiometric ECL biosensors based on particular ECL materials and ratiometric sensing strategies.
比率型电化学发光（ECL）分析因其消除了外部干扰并提高了检测的可靠性，已被广泛应用于生物传感领域。为了构建具有高灵敏度和可靠性的比率型 ECL 生物传感器，找到具有合适应用电位或发射波长的两个信号发射器至关重要。本综述旨在讨论基于 ECL 材料和相应的比率型传感方法的比率型 ECL 生物传感器的最新进展和趋势。我们重点介绍了基于特定 ECL 材料和比率型传感策略的四种类型的比率型 ECL 生物传感器。
