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电化学发光生物传感器在真菌毒素分析中的最新进展。

Recent Advances in Electrochemiluminescence Biosensors for Mycotoxin Assay.

机构信息

Department of Chemistry, College of Sciences, Nanjing Agricultural University, 1 Weigang, Nanjing 210095, China.

出版信息

Biosensors (Basel). 2023 Jun 14;13(6):653. doi: 10.3390/bios13060653.

DOI:10.3390/bios13060653
PMID:37367018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10296450/
Abstract

Rapid and efficient detection of mycotoxins is of great significance in the field of food safety. In this review, several traditional and commercial detection methods are introduced, such as high-performance liquid chromatography (HPLC), liquid chromatography/mass spectrometry (LC/MS), enzyme-linked immunosorbent assay (ELISA), test strips, etc. Electrochemiluminescence (ECL) biosensors have the advantages of high sensitivity and specificity. The use of ECL biosensors for mycotoxins detection has attracted great attention. According to the recognition mechanisms, ECL biosensors are mainly divided into antibody-based, aptamer-based, and molecular imprinting techniques. In this review, we focus on the recent effects towards the designation of diverse ECL biosensors in mycotoxins assay, mainly including their amplification strategies and working mechanism.

摘要

快速有效地检测真菌毒素在食品安全领域具有重要意义。在本综述中，介绍了几种传统和商业检测方法，如高效液相色谱（HPLC）、液相色谱/质谱（LC/MS）、酶联免疫吸附测定（ELISA）、检测条等。电化学发光（ECL）生物传感器具有灵敏度高、特异性好的优点。因此，ECL 生物传感器在真菌毒素检测中的应用引起了广泛关注。根据识别机制，ECL 生物传感器主要分为基于抗体、基于适体和分子印迹技术。本综述主要关注近年来设计用于真菌毒素检测的各种 ECL 生物传感器的最新效果，包括其放大策略和工作机制。

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