系统性硬化症的心血管并发症：需要注意的问题。

Cardiovascular complications of systemic sclerosis: What to look for.

机构信息

Department of Cardiovascular Medicine, Cleveland Clinic; Clinical Instructor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OHDepartment of Cardiovascular Medicine, Cleveland ClinicDepartment of Rheumatic and Immunologic Diseases, Cleveland Clinic; Associate Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OHDepartment of Cardiovascular Medicine, Cleveland Clinic; Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH

出版信息

Cleve Clin J Med. 2019 Oct;86(10):685-695. doi: 10.3949/ccjm.86a.18109.

DOI:10.3949/ccjm.86a.18109

PMID:31597076

Abstract

Systemic sclerosis, an autoimmune disease characterized by fibrosis of the skin and various internal organs, is associated with cardiovascular abnormalities including pulmonary hypertension, atherosclerosis, right and left ventricular dysfunction, arrhythmias, conduction defects, pericardial disease, and valvular heart disease. Clinicians caring for patients with this disease should regularly screen for cardiac symptoms, and patients with abnormal findings should be managed in conjunction with a cardiologist to optimally modify cardiovascular risks.

摘要

系统性硬化症是一种自身免疫性疾病，其特征是皮肤和各种内部器官纤维化，与心血管异常有关，包括肺动脉高压、动脉粥样硬化、左右心室功能障碍、心律失常、传导缺陷、心包疾病和瓣膜性心脏病。治疗这种疾病的临床医生应定期筛查心脏症状，对于有异常发现的患者，应与心脏病专家共同管理，以最佳地调整心血管风险。