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大麻素在皮肤科的潜在作用。

The potential role of cannabinoids in dermatology.

机构信息

The Royal Prince Alfred Hospital, Sydney, Australia.

Icahn School of Medicine at Mount Sinai, New York, NY, USA.

出版信息

J Dermatolog Treat. 2020 Dec;31(8):839-845. doi: 10.1080/09546634.2019.1675854. Epub 2019 Oct 10.

DOI:10.1080/09546634.2019.1675854
PMID:31599175
Abstract

Cannabis is increasingly being used world-wide to treat a variety of dermatological conditions. Medicinal cannabis is currently legalized in Canada, 31 states in America and 19 countries in Europe. The authors reviewed the literature on the pharmacology and use of cannabinoids in treating a variety of skin conditions including acne, atopic dermatitis, psoriasis, skin cancer, pruritus, and pain. Cannabinoids have demonstrated anti-inflammatory, antipruritic, anti-ageing, and antimalignancy properties by various mechanisms including interacting with the newly found endocannabinoid system of the skin thereby providing a promising alternative to traditional treatments.

摘要

大麻在世界范围内被越来越多地用于治疗各种皮肤科疾病。医用大麻目前在加拿大、美国的 31 个州和欧洲的 19 个国家合法化。作者回顾了关于大麻素治疗各种皮肤疾病(包括痤疮、特应性皮炎、银屑病、皮肤癌、瘙痒和疼痛)的药理学和用途的文献。大麻素通过各种机制显示出抗炎、止痒、抗老化和抗恶性的特性,包括与新发现的皮肤内源性大麻素系统相互作用,从而为传统治疗提供了有前途的替代方案。

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The potential role of cannabinoids in dermatology.大麻素在皮肤科的潜在作用。
J Dermatolog Treat. 2020 Dec;31(8):839-845. doi: 10.1080/09546634.2019.1675854. Epub 2019 Oct 10.
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