John F. Kennedy School of Government, Harvard University, Cambridge, Massachusetts.
School of Life Sciences, Arizona State University, Tempe, Arizona.
CRISPR J. 2019 Oct;2(5):266-271. doi: 10.1089/crispr.2019.0047.
An international regulatory commission convened by scientific academies is a premature and problematic approach to governing human germline genome editing. Given the complex, international landscape of genome editing and significant cross-national differences among regulatory cultures, deferring to a single commission to set the agenda for global governance raises troublesome questions of framing and representation. Rather, democratic governance on a global level demands a new mechanism for active, sustained reflection by scientists on their own practices, conducted in partnership with scholars from other disciplines, as well as public representatives from varied social, political, and religious backgrounds. To be legitimate, ideas of the right form of governance in this emerging and highly consequential area of research need to be opened up to a wider diversity of views and voices.
由科学学术机构召集的国际监管委员会是一种不成熟且有问题的人类生殖系基因组编辑治理方法。鉴于基因组编辑的复杂、国际化格局以及监管文化之间存在的重大跨国差异,将全球治理的议程交由单一委员会来决定,引发了框架和代表性方面的棘手问题。相反,全球层面的民主治理需要一种新的机制,让科学家们与其他学科的学者以及来自不同社会、政治和宗教背景的公众代表合作,对自身实践进行积极、持续的反思。为了使其具有合法性,在这一新兴且极具深远影响的研究领域,对于恰当治理形式的看法需要向更广泛的不同观点和声音开放。