Spears J R, Marais H J, Serur J, Pomerantzeff O, Geyer R P, Sipzener R S, Weintraub R, Thurer R, Paulin S, Gerstin R, Grossman W
J Am Coll Cardiol. 1983 May;1(5):1311-4. doi: 10.1016/s0735-1097(83)80145-4.
The feasibility of in vivo coronary angioscopy was tested utilizing a 1.8 mm angioscope in vessels where blood had been replaced by optically clear liquids, including a new perfluorocarbon emulsion. After trials in postmortem canine and human coronary arteries, in vivo intraluminal visualization was accomplished in the dog with a catheterization technique and in patients during open heart surgery. The results demonstrate the feasibility and potential clinical usefulness of direct visualization of intravascular anatomy and disease, analogous to endoscopy of other organ systems.
利用1.8毫米血管内窥镜，在血管内血液已被包括新型全氟碳乳剂在内的光学透明液体替代的情况下，测试了体内冠状动脉血管内窥镜检查的可行性。在对犬类和人类冠状动脉进行尸检试验后，通过导管插入技术在犬类身上实现了体内腔内可视化，在心脏直视手术患者中也实现了体内腔内可视化。结果表明，直接观察血管内解剖结构和疾病具有可行性和潜在的临床实用性，类似于其他器官系统的内窥镜检查。
