Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, China.
Department of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, China.
Chem Commun (Camb). 2019 Oct 24;55(86):12980-12983. doi: 10.1039/c9cc06210f.
Nuclear factor kappa B p50 (NF-κB p50) induces various biological processes. In this study, a highly selective and sensitive electrochemiluminescence (ECL) biosensor for the detection of NF-κB p50 has been developed, which combines the high selectivity of the proximity hybridization assay (PHA) with the high efficiency of the hybridization chain reaction (HCR).
核因子 kappa B p50（NF-κB p50）诱导各种生物过程。在这项研究中，开发了一种高选择性和高灵敏度的电化学发光（ECL）生物传感器，用于检测 NF-κB p50，该传感器结合了近邻杂交分析（PHA）的高选择性和杂交链反应（HCR）的高效率。
