Milani-Nejad Nima, Kaffenberger Jessica
J Drugs Dermatol. 2019 Oct 1;18(10):1047.
To the Editor: Acrodermatitis continua of Hallopeau (ACH) is a relatively rare chronic disorder with clinical findings of pustules and erythematous plaques on the digits.1 Although it is a variant of pustular psoriasis, it can be resistant to multiple lines of therapy. We describe for the first time a patient with recalcitrant ACH successfully treated with brodalumab, an interleukin-17 receptor A (IL-17RA) blocking antibody.
哈洛佩奥连续性肢端皮炎（ACH）是一种相对罕见的慢性疾病，临床表现为手指上出现脓疱和红斑性斑块。虽然它是脓疱型银屑病的一种变体，但可能对多种治疗方法耐药。我们首次描述了一名顽固性ACH患者成功接受布罗达单抗（一种白细胞介素-17受体A（IL-17RA）阻断抗体）治疗的病例。
