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有化学感觉功能障碍主诉患者的健康史和医学评估。

Health histories and medical evaluations of patients with complaints of chemosensory dysfunction.

作者信息

Bromley Steven M, Doty Richard L

机构信息

South Jersey MS Center and Bromley Neurology, PC Audubon, NJ, United States.

Smell and Taste Center and Department of Otorhinolaryngology: Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

出版信息

Handb Clin Neurol. 2019;164:219-227. doi: 10.1016/B978-0-444-63855-7.00014-9.

DOI:10.1016/B978-0-444-63855-7.00014-9
PMID:31604549
Abstract

Key elements for understanding, assessing, and treating a patient with a complaint of chemosensory dysfunction include establishing a relevant medical history and performing a focused medical examination. This age-old medical approach combines the utilization of associated tests and the results of chemosensory testing to establish a diagnosis and plan for medical management. Chemosensory testing is critical to establish the degree of dysfunction, the veracity and accuracy of a patient's self-report, the efficacy of treatments, and the degree to which spontaneous recovery occurs. In common with most medical disorders, it is incumbent upon the physician to determine, as best as possible, the time of onset of the symptom, its severity, precipitating factors, comorbidities, and fluctuations over time to understand the underlying pathophysiology. Importantly, distinguishing between "taste" loss due to decreased flavor sensations secondary to olfactory system compromise and "taste" loss due to true taste bud-mediated sensory alterations is critical. Unfortunately, this distinction is often underappreciated by medical professionals and laypersons alike, resulting in needless referrals within the medical community, including those related to imaging and gastroenterological testing. This chapter outlines the basic elements of the medical history and assessment of patients with complaints of chemosensory dysfunction, including a discussion on how to detect malingering.

摘要

理解、评估和治疗主诉化学感觉功能障碍患者的关键要素包括建立相关病史并进行针对性的体格检查。这种古老的医学方法结合了相关检查的运用以及化学感觉测试的结果,以确立诊断并制定医疗管理计划。化学感觉测试对于确定功能障碍的程度、患者自我报告的真实性和准确性、治疗效果以及自发恢复的程度至关重要。与大多数医学病症一样,医生有责任尽可能确定症状的发作时间、严重程度、诱发因素、合并症以及随时间的波动情况,以了解潜在的病理生理学。重要的是,区分因嗅觉系统受损导致味觉感受减退引起的“味觉”丧失和因真正的味蕾介导的感觉改变引起的“味觉”丧失至关重要。不幸的是,这种区别往往未得到医学专业人员和外行人的充分重视,导致在医疗界进行不必要的转诊,包括那些与影像学和胃肠病学检查相关的转诊。本章概述了主诉化学感觉功能障碍患者的病史和评估的基本要素,包括关于如何检测伪装的讨论。

相似文献

1
Health histories and medical evaluations of patients with complaints of chemosensory dysfunction.有化学感觉功能障碍主诉患者的健康史和医学评估。
Handb Clin Neurol. 2019;164:219-227. doi: 10.1016/B978-0-444-63855-7.00014-9.
2
Psychophysical testing of smell and taste function.嗅觉和味觉功能的心理物理学测试。
Handb Clin Neurol. 2019;164:229-246. doi: 10.1016/B978-0-444-63855-7.00015-0.
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Chemosensory function and dysfunction.化学感应功能与功能障碍。
Crit Rev Oral Biol Med. 1998;9(3):267-91. doi: 10.1177/10454411980090030201.
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Disorders of smell and taste.嗅觉和味觉障碍。
Med Clin North Am. 1999 Jan;83(1):57-74. doi: 10.1016/s0025-7125(05)70087-0.
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Disorders of taste and smell.味觉和嗅觉障碍。
J La State Med Soc. 1994 Oct;146(10):433-7.
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[Smell and taste disorders].[嗅觉和味觉障碍]
Schweiz Med Wochenschr. 1999 Jul 13;129(27-28):1039-46.
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Decreased electrogustometric taste sensitivity in patients with acquired olfactory dysfunction.味觉敏感性检测在获得性嗅觉功能障碍患者中的变化。
Rhinology. 2018 Jun 1;56(2):158-165. doi: 10.4193/Rhin17.186.
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Systemic diseases and disorders.全身性疾病和病症。
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Clinical assessment of patients with smell and taste disorders.嗅觉和味觉障碍患者的临床评估。
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Smell and taste disorders: a primary care approach.嗅觉和味觉障碍:初级保健方法
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Taste dysfunction as a predictor of depression in schizophrenia: A systematic review and meta-analysis.味觉障碍作为精神分裂症患者抑郁的预测因子:系统评价和荟萃分析。
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2
Gustatory event-related potential alterations in olfactory dysfunction patients.味觉事件相关电位在嗅觉功能障碍患者中的改变。
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Assessment of Taste Function.味觉功能评估。
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