School of Biological Sciences, University of Western Australia, Perth, WA, 6009, Australia.
School of Biological Sciences, University of Western Australia, Perth, WA, 6009, Australia.
Trends Plant Sci. 2019 Dec;24(12):1137-1150. doi: 10.1016/j.tplants.2019.08.007. Epub 2019 Oct 8.
Crop diseases, in conjunction with climate change, are a major threat to global crop production. DNA methylation is an epigenetic mark and is involved in plants' biological processes, including development, stress adaptation, and genome evolution. By providing a new source of variation, DNA methylation introduces novel direction to both scientists and breeders with its potential in disease resistance enhancement. Here, we discuss the impact of pathogen-induced DNA methylation modifications on a host's transcriptome reprogramming and genome stability, as part of the plant's defense mechanisms. We also highlight the knowledge gaps that need to be investigated for understanding the entire role of DNA methylation in plant pathogen interactions. This will ultimately assist breeders toward improving resistance and decreasing yield losses.
作物病害与气候变化一起，是全球作物生产的主要威胁。DNA 甲基化是一种表观遗传标记，参与植物的生物过程，包括发育、应激适应和基因组进化。通过提供新的变异来源，DNA 甲基化在增强抗病性方面为科学家和培育者提供了新的方向。在这里，我们讨论了病原体诱导的 DNA 甲基化修饰对宿主转录组重编程和基因组稳定性的影响，这是植物防御机制的一部分。我们还强调了需要研究的知识空白，以了解 DNA 甲基化在植物与病原体相互作用中的全部作用。这最终将有助于培育者提高抗性，减少产量损失。
